Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2206168 | 0.89 | ALDH1A1 (0.40) | HSD11B1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL4525933 | 0.86 | HSD11B1 (0.41) | HSD11B1OPRM1OPRD1OPRK1ROCK2 | |
| SCHEMBL3002570 | 0.85 | HSD11B1 (0.57) | HSD11B1OPRM1OPRD1OPRK1ALDH1A1 | |
| SCHEMBL4523771 | 0.84 | HSD11B1 (0.45) | HSD11B1OPRM1OPRD1OPRK1ROCK2 | |
| SCHEMBL4504298 | 0.84 | ALDH1A1 (0.34) | HSD11B1GRIN1GRIN2BOPRM1OPRD1 | |
| SCHEMBL2235214 | 0.84 | ATM (0.42) | HSD11B1ALDH1A1CACNB4CACNA1ACACNA1G | |
| SCHEMBL4500714 | 0.84 | HSD11B1 (0.45) | HSD11B1ALDH1A1CACNB4CACNA1ACACNA1G | |
| SCHEMBL2209243 | 0.83 | ALDH1A1 (0.46) | HSD11B1ALDH1A1GAAMEN1CYP3A4 | |
| SCHEMBL2210485 | 0.82 | SMN1; SMN2 (0.41) | HSD11B1OPRM1OPRK1ALDH1A1CACNB4 | |
| SCHEMBL4515408 | 0.82 | HSD11B1 (0.37) | HSD11B1OPRK1ALDH1A1CACNB4CACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | HSD11B1 1/4885GRIN1 1622/4885GRIN2B 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.