⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3078068 | 0.81 | — | — | |
| SCHEMBL17201196 | 0.78 | — | — | |
| SCHEMBL17799 | 0.78 | — | — | |
| SCHEMBL28587025 | 0.77 | ALDH1A1 (0.49) | — | |
| SCHEMBL245979 | 0.77 | ALDH1A1 (0.49) | — | |
| Hydrochloric Acid SCHEMBL244808 | 0.76 | GAA (0.50) | — | |
| Hydrochloric Acid SCHEMBL7501190 | 0.76 | GAA (0.50) | — | |
| SCHEMBL2643692 | 0.76 | — | — | |
| SCHEMBL244807 | 0.76 | GAA (0.50) | — | |
| SCHEMBL4166547 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746355-B | Phenylpyrazole compound, pharmaceutical composition, and preparation method and application thereof | 中国科学院上海有机化学研究所 | 2023-08-11 | — | — | CN | claimed |
| CN-110746355-A | Phenylpyrazole compound, pharmaceutical composition, preparation method and application thereof | 中国科学院上海有机化学研究所 | 2020-02-04 | — | — | CN | claimed |
| EP-3275877-A1 | HERBICIDAL PYRIDINE COMPOUNDS | BASF SE (DE) | 2018-01-31 | — | — | EP | claimed |
| EP-2310009-B1 | PARENTERAL AND ORAL FORMULATIONS OF BENZIMIDAZOLES | UNIV HOUSTON (US) | 2017-12-20 | — | — | EP | claimed |
| EP-2334175-B1 | PHENYL-SUBSTITUTED BICYCLOOCTANE 1,3 DIONE DERIVATIVES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | claimed |
| US-9259391-B2 | Parenteral and oral formulations of benzimidazoles | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2016-02-16 | — | — | US | claimed |
| US-9259390-B2 | Parenteral and oral formulations of benzimidazoles | THE UNIVERSITY OF HOUSTON SYSTEM (US) | 2016-02-16 | — | — | US | claimed |
| US-8907096-B2 | N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase | HIGH POINT PHARMACEUTICALS, LLC (US) | 2014-12-09 | — | — | US | claimed |
| US-20140357633-A1 | COMPOUNDS FOR INHIBITING THE INTERACTION OF BCL2 WITH BINDING PARTNERS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2014-12-04 | — | — | US | claimed |
| EP-2794592-A1 | COMPOUNDS FOR INHIBITING THE INTERACTION OF BCL2 WITH BINDING PARTNERS | Novartis AG (CH) | 2014-10-29 | — | — | EP | claimed |
| EP-0680472-A1 | 4,5-DIPHENYLIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ACYL COENZYME A: CHOLESTEROL-0-ACYL-TRANSFERASE (ACAT) INHIBITOR | PHARMACIA & UPJOHN S.p.A. (IT) | 1995-11-08 | — | — | EP | claimed |
| WO-1995014673-A1 | 4,5-DIPHENYLIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ACYL COENZYME A: CHOLESTEROL-0-ACYL-TRANSFERASE (ACAT) INHIBITOR | PHARMACIA S.P.A. (IT) | 1995-06-01 | — | — | WO | claimed |
| EP-0628036-A4 | N-SUBSTITUTED-FURYLALKENYL HYDROXAMIC ACID AND N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY. | — | 1995-01-11 | — | — | EP | claimed |
| EP-0628036-A1 | N-SUBSTITUTED-FURYLALKENYL HYDROXAMIC ACID AND N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1994-12-14 | — | — | EP | claimed |
| WO-1993017006-A1 | N-SUBSTITUTED-FURYLALKENYL HYDROXAMIC ACID AND N-HYDROXYUREA COMPOUNDS HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LABORATORIES (US) | 1993-09-02 | — | — | WO | claimed |
| US-5169854-A | N-substituted-furylalkenyl hydroxamic acid and N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1992-12-08 | — | — | US | claimed |
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | claimed |
| US-4904777-A | COLORFASTNESS | BASF AKTIENGESELLSCHAFT (DE) | 1990-02-27 | — | — | US | claimed |
| EP-0054974-B1 | IMIDAZOLYLPROPANOL COMPOUNDS AND THEIR ACID ADDITION SALTS, AND PRODUCTION AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-07-10 | — | — | EP | claimed |
| US-4016263-A | BACTERICIDES | BOEHRINGER INGELHEIM GMBH (DT) | 1977-04-05 | — | — | US | claimed |