Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506572 | 0.85 | HSD11B1 (0.45) | HSD11B1SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL4514552 | 0.83 | HSD11B1 (0.48) | HSD11B1SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL2989122 | 0.83 | HSD11B1 (0.48) | HSD11B1SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL2989117 | 0.83 | HSD11B1 (0.48) | HSD11B1SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL4523656 | 0.83 | P2RX7 (0.46) | BTKSMN1; SMN2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL4512811 | 0.82 | HSD11B1 (0.45) | HSD11B1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL4505857 | 0.81 | HSD11B1 (0.44) | HSD11B1SMN1; SMN2KDM4EALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL4516692 | 0.81 | HSD11B1 (0.44) | HSD11B1SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL4511224 | 0.81 | HSD11B1 (0.46) | HSD11B1SMN1; SMN2KDM4ETSHRPOLB | |
| SCHEMBL4511941 | 0.81 | HSD11B1 (0.46) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | HSD11B1 1/4885BTK 3901/4885SMN1; SMN2 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.