Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515074 | 1.00 | ALDH1A1 (0.42) | ALDH1A1HTTNPC1CYP3A4CYP2D6 | |
| SCHEMBL1903978 | 0.91 | L3MBTL1 (0.42) | ALDH1A1NPC1POLBSMN1; SMN2TSHR | |
| SCHEMBL14152197 | 0.91 | L3MBTL1 (0.42) | ALDH1A1NPC1POLBSMN1; SMN2TSHR | |
| SCHEMBL14151907 | 0.91 | L3MBTL1 (0.42) | ALDH1A1NPC1POLBSMN1; SMN2TSHR | |
| SCHEMBL11088727 | 0.89 | ALDH1A1 (0.45) | ALDH1A1HTTPOLBSMN1; SMN2TSHR | |
| SCHEMBL22982975 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HTTNPC1CYP3A4CYP2D6 | |
| SCHEMBL2607044 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1HTTCYP2D6POLBSMN1; SMN2 | |
| SCHEMBL19946953 | 0.82 | CHRM1 (0.34) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL771790 | 0.82 | GLS (0.50) | ALDH1A1CYP2C9HPGDKDM4E | |
| SCHEMBL6404713 | 0.82 | GLS (0.50) | ALDH1A1CYP2C9HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504432-B2 | Ester derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| US-20070129397-A1 | Ester derivatives | MSD K.K. (JP) | 2007-06-07 | — | — | US | disclosed |
| US-7192969-B2 | Ester derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20050065211-A1 | Ester derivatives | MSD K.K. (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1302458-A1 | ESTER DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129397-A1 | Ester derivatives | CHRM3, CHRM2, CHRM1 | ALDH1A1 1398/4885HTT 3726/4885NPC1 1025/4885 |
| US-20050065211-A1 | Ester derivatives | CHRM3, CHRM2, CHRM1 | ALDH1A1 1386/4885HTT 3708/4885NPC1 1025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.