SCHEMBL451525

SCHEMBL451525

CCCC(=O)CC(=O)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 2/20 0.46
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
HDAC3 O15379 4/20 0.43
HDAC1 Q13547 4/20 0.43
HDAC2 Q92769 4/20 0.43
HDAC8 Q9BY41 4/20 0.43
HDAC6 Q9UBN7 1/20 0.43
FFAR3 O14843 4/20 0.43
CTSD P07339 1/20 0.42
TSHR P16473 1/20 0.41
HAO1 Q9UJM8 1/20 0.38
KDM4E B2RXH2 1/20 0.35
KDM6B O15054 1/20 0.35
KDM5C P41229 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
CASP2 P42575 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29587080 0.97 TDP1 (0.47) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL13500515 0.97 TDP1 (0.47) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL28721169 0.97 TDP1 (0.47) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL29063083 0.95 TDP1 (0.45) TDP1ALDH1A1CES2CES1HDAC3
Methylamine SCHEMBL27489986 0.92 TDP1 (0.43) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL1701664 0.91 CES2 (0.53) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL3028863 0.90 KDM4E (0.50) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL11434918 0.88 CES2 (0.50) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL29053185 0.88 CES2 (0.50) TDP1ALDH1A1CES2CES1HDAC3
SCHEMBL3126473 0.88 CES2 (0.50) TDP1ALDH1A1CES2CES1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 438 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924651-A Polyurethane resin and fiber reinforced composite material, and preparation method and application thereof 南京聚发新材料有限公司 2024-04-26 CN claimed
EP-3727686-B1 MOISTURE-CURABLE COMPOSITIONS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-05-10 EP claimed
EP-2935490-B1 ORGANOPOLYSILOXANE COMPOSITION SUITABLE FOR VULCANISATION INTO AN ELASTOMER AT ROOM TEMPERATURE AND NEW ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS ELKEM SILICONES FRANCE SAS (FR) 2022-12-21 EP claimed
EP-3474046-B1 POLYMERIZABLE COMPOSITION FOR A MAKING A PLASTIC LENS AND PROCESS FOR PREPARING SUCH A LENS SKC CO LTD (KR) 2022-11-30 EP claimed
CN-107075120-B Silicone composition crosslinking catalyst 埃肯有机硅法国有限公司 2021-02-26 CN claimed
EP-3385304-B1 ORGANOPOLYSILOXANE COMPOSITION WHICH CAN BE VULCANISED AT AMBIENT TEMPERATURE IN ELASTOMER ELKEM SILICONES FRANCE SAS (FR) 2020-07-15 EP claimed
CN-107207733-B Novel crosslinking catalysts for silicone compositions 埃肯有机硅法国简易股份公司 2020-07-14 CN claimed
CN-107001634-B Crosslinking catalysts for silicone compositions 埃肯有机硅法国简易股份公司 2020-04-24 CN claimed
CN-110845987-A High-performance copolyamide hot melt adhesive composition 南通协鑫热熔胶有限公司 2020-02-28 CN claimed
US-10308770-B2 Silicone composition crosslinking catalysts ELKEN SILICONES FRANCE SAS (FR) 2019-06-04 US claimed
US-20110021684-A1 RTV-ORGANOPOLYSILOXANE COMPOSITIONS AND NOVEL ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS THEREFOR BLUESTAR SILICONES FRANCE (FR) 2011-01-27 US claimed
US-20100324213-A1 RTV-ORGANOPOLYSILOXANE COMPOSITIONS AND NOVEL ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS THEREFOR BLUESTAR SILICONES FRANCE (FR) 2010-12-23 US claimed
US-6235101-B1 SILICON HYDROLYZATE, METAL CHELATE, ORGANIC SOLVENT AND BETA DIKETONE FOR FILMS JSR CORPORATION (JP) 2001-05-22 US claimed
EP-0921561-A2 Composition for film formation and film JSR Corporation (JP) 1999-06-09 EP claimed
EP-0772609-B1 CYCLIC KETONE PEROXIDE FORMULATIONS AKZO NOBEL NV (NL) 1999-02-24 EP claimed
US-5808110-A TRANSPORTABLE; STORAGE STABLE AKZO NOBEL NV (NL) 1998-09-15 US claimed
EP-0772609-A1 CYCLIC KETONE PEROXIDE FORMULATIONS Akzo Nobel N.V. (NL) 1997-05-14 EP claimed
WO-1996003397-A1 CYCLIC KETONE PEROXIDE FORMULATIONS AKZO NOBEL N.V. (NL) 1996-02-08 WO claimed
EP-0387118-B1 Process for the condensation of at least one epoxide with at least one cyclic anhydride in the presence of a catalyst based on at least one titanium complex INST FRANCAIS DU PETROLE (FR) 1994-04-20 EP claimed
EP-0299413-A1 New tetramethyl-cis-diaza-bicyclo[4.2.0]octane-3,5-dione derivatives having a differentiation-inducing activity MEIJI SEIKA KAISHA LTD. (JP) 1989-01-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100324213-A1 RTV-ORGANOPOLYSILOXANE COMPOSITIONS AND NOVEL ORGANOPOLYSILOXANE POLYCONDENSATION CATALYSTS THEREFOR IDUA, MAN2B1, RNASE1 TDP1 967/4885ALDH1A1 2150/4885CES2 644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.