Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126473 | 0.97 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL5667473 | 0.97 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL11434918 | 0.97 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL29053185 | 0.97 | CES2 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL8101925 | 0.94 | CES2 (0.47) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL451525 | 0.91 | TDP1 (0.50) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL28721169 | 0.88 | TDP1 (0.47) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL534886 | 0.88 | CES1 (0.52) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL13500515 | 0.88 | TDP1 (0.47) | CES2CES1HDAC3HDAC1HDAC2 | |
| SCHEMBL29587080 | 0.88 | TDP1 (0.47) | CES2CES1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051507-A1 | Polyol Composition | COVESTRO DEUTSCHLAND AG (DE) | 2025-02-13 | — | — | US | claimed |
| EP-4267643-B1 | A METHOD FOR STABLY STORING AN ISOCYANATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2025-01-01 | — | — | EP | claimed |
| US-12162977-B2 | Blocked polyisocyanate crosslinking agent, its preparation method and a coating composition comprising the same | BASF COATINGS GMBH (DE) | 2024-12-10 | — | — | US | claimed |
| EP-4448609-A1 | POLYOL COMPOSITION | Covestro Deutschland AG (DE) | 2024-10-23 | — | — | EP | claimed |
| US-20240124680-A1 | A METHOD FOR STABLY STORING AN ISOCYANATE COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2024-04-18 | — | — | US | claimed |
| CN-114729100-B | Blocked polyisocyanate crosslinking agent, process for producing the same and coating composition comprising the same | 巴斯夫涂料有限公司 | 2024-04-16 | — | — | CN | claimed |
| EP-4267643-A1 | A METHOD FOR STABLY STORING AN ISOCYANATE COMPOSITION | Covestro Deutschland AG (DE) | 2023-11-01 | — | — | EP | claimed |
| EP-4227339-A1 | POLYOL COMPOSITION | Covestro Deutschland AG (DE) | 2023-08-16 | — | — | EP | claimed |
| CN-116601141-A | Method for stably storing isocyanate composition | 科思创德国股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| WO-2023110560-A1 | POLYOL COMPOSITION | COVESTRO DEUTSCHLAND AG (DE) | 2023-06-22 | — | — | WO | claimed |
| US-20160068618-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2016-03-10 | — | — | US | claimed |
| US-20140275400-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | SIRRUS, INC. | 2014-09-18 | — | — | US | claimed |
| EP-2768897-A2 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | Bioformix Inc. (US) | 2014-08-27 | — | — | EP | claimed |
| WO-2013059479-A2 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | BIOFORMIX INC. (US) | 2013-04-25 | — | — | WO | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
| EP-0912467-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998000375-A1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE (FR) | 1998-01-08 | — | — | WO | claimed |
| US-4537920-A | 4H-1-benzopyrans and lubricant compositions containing same | ETHYL CORPORATION (US) | 1985-08-27 | — | — | US | claimed |
| US-4456770-A | Chemical process for preparing 1,3 diketones | ETHYL CORPORTATION (US) | 1984-06-26 | — | — | US | claimed |
| US-4456771-A | Chemical process for preparing 1,3-diketones | ETHYL CORPORATION (US) | 1984-06-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124680-A1 | A METHOD FOR STABLY STORING AN ISOCYANATE COMPOSITION | IDH3A, IDH1, IDH2 | CES2 347/4885CES1 3499/4885HDAC3 386/4885 |
| US-20140275400-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | BCKDK, ILK, PKM | CES2 3761/4885CES1 3934/4885HDAC3 3845/4885 |
| US-20160068618-A1 | METHYLENE BETA-DIKETONE MONOMERS, METHODS FOR MAKING METHYLENE BETA-DIKETONE MONOMERS, POLYMERIZABLE COMPOSITIONS AND PRODUCTS FORMED THEREFROM | MSMO1, PKM, KHK | CES2 3526/4885CES1 3525/4885HDAC3 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.