Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212004 | 0.77 | TXNRD1 (0.58) | ALDH1A1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL31040685 | 0.77 | TXNRD1 (0.58) | ALDH1A1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL29642602 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ABCHEACHE | |
| SCHEMBL2230388 | 0.76 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ABCHEACHE | |
| Ammonia Solution, Strong SCHEMBL28747081 | 0.75 | ALDH1A1 (0.96) | ALDH1A1MEN1KMT2ABCHEACHE | |
| Methane SCHEMBL28038323 | 0.75 | ALDH1A1 (0.96) | ALDH1A1MEN1KMT2ABCHEACHE | |
| SCHEMBL1012937 | 0.75 | BAZ1A (0.60) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL30626616 | 0.75 | BAZ1A (0.60) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| Quinoline SCHEMBL28125811 | 0.75 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ABCHEACHE | |
| SCHEMBL31378665 | 0.74 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090240055-A1 | Method for 1H-Imidazo[4,5-C] Pyridines and Analogs Thereof | KREPSKI LARRY R | 2009-09-24 | — | — | US | disclosed |
| CN-101312975-A | Method for 1h-imidazo[4,5-c]pyridines and analogs thereof | COLEY PHARM GROUP INC (US) | 2008-11-26 | — | — | CN | disclosed |
| EP-1937683-A1 | METHOD FOR 1H-IMIDAZOÝ4,5-c¨PYRIDINES AND ANALOGS THEREOF | Coley Pharmaceutical Group, Inc. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007035935-A1 | METHOD FOR 1H-IMIDAZO[4,5-c]PYRIDINES AND ANALOGS THEREOF | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240055-A1 | Method for 1H-Imidazo[4,5-C] Pyridines and Analogs Thereof | CYP4B1, CYP4F8, CYP4X1 | ALDH1A1 483/4885MEN1 205/4885KMT2A 2015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.