Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.54 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509555 | 0.87 | SCN9A (0.54) | SCN9ARBP4CHEK2ALOX5APFEN1 | |
| SCHEMBL4510139 | 0.87 | STS (0.47) | RBP4FNTAFNTBMEN1KMT2A | |
| SCHEMBL17729089 | 0.85 | CHEK2 (0.56) | SCN9AFNTAFNTBCHEK2ALOX5AP | |
| SCHEMBL2069204 | 0.82 | CHEK2 (0.59) | SCN9AFNTAFNTBCHEK2ALOX5AP | |
| SCHEMBL16771013 | 0.81 | SCN9A (0.64) | SCN9ACHEK2ALOX5APFEN1 | |
| SCHEMBL16771031 | 0.81 | SCN9A (0.64) | SCN9ACHEK2ALOX5APFEN1 | |
| SCHEMBL17061869 | 0.81 | SCN9A (0.64) | SCN9ACHEK2ALOX5APFEN1 | |
| SCHEMBL3099116 | 0.81 | RBP4 (0.67) | SCN9ARBP4ALOX5APFEN1ALDH1A1 | |
| SCHEMBL4499579 | 0.81 | RBP4 (0.53) | SCN9ARBP4ALOX5APFEN1HTR6 | |
| SCHEMBL27157955 | 0.81 | SCN9A (0.55) | SCN9ARBP4CHEK2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SCN9A 1620/4885RBP4 1872/4885FNTA 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.