Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.41 |
| ▸ | SCD | O00767 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4501251 | 0.91 | ALDH1A1 (0.49) | MAPTSMN1; SMN2ALDH1A1KMT2ATDP1 | |
| SCHEMBL4515634 | 0.89 | SMN1; SMN2 (0.44) | MAPTSMN1; SMN2ALDH1A1KMT2ATDP1 | |
| SCHEMBL4509650 | 0.89 | ALDH1A1 (0.53) | MAPTSMN1; SMN2ALDH1A1KMT2ASCD5 | |
| SCHEMBL23241876 | 0.88 | KMT2A (0.52) | SMN1; SMN2ALDH1A1KMT2ATDP1SCD5 | |
| SCHEMBL4504925 | 0.87 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2ALDH1A1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL4517307 | 0.87 | KMT2A (0.51) | SMN1; SMN2ALDH1A1KMT2ATDP1SCD5 | |
| Hydrochloric Acid SCHEMBL4517235 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1SCD5SCD | |
| SCHEMBL4507518 | 0.82 | SMN1; SMN2 (0.51) | MAPTSMN1; SMN2ALDH1A1KMT2ATDP1 | |
| SCHEMBL4492672 | 0.81 | ALDH1A1 (0.53) | MAPTSMN1; SMN2ALDH1A1KMT2ASCD5 | |
| SCHEMBL4493419 | 0.81 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2ALDH1A1KMT2ASCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | MAPT 4022/4885SMN1; SMN2 2075/4885ALDH1A1 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.