Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31396449 | 0.83 | PIK3CA (0.45) | MEN1KMT2AGAANPC1RAB9A | |
| SCHEMBL12134343 | 0.76 | SYK (0.53) | SYKLTB4RMAP4K4AAK1DYRK1A | |
| SCHEMBL4532204 | 0.76 | CIT (0.42) | PAX8DUSP10CYP3A4PKM | |
| SCHEMBL1881782 | 0.76 | SSTR4 (0.37) | SYKPAX8MEN1KMT2AAAK1 | |
| SCHEMBL28481850 | 0.75 | AAK1 (0.49) | AAK1CYP3A4 | |
| SCHEMBL24529116 | 0.75 | SSTR4 (0.41) | SYKPAX8AAK1NPC1RAB9A | |
| SCHEMBL16806443 | 0.75 | ATR (0.41) | SYKPAX8KMT2APOLBAAK1 | |
| SCHEMBL30226544 | 0.75 | ATR (0.41) | SYKPAX8KMT2APOLBAAK1 | |
| SCHEMBL4529959 | 0.74 | PAX8 (0.37) | PAX8POLBDUSP10ALDH1A1MAPT | |
| SCHEMBL4519488 | 0.74 | MAP4K4 (0.36) | SYKPAX8MEN1KMT2AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208098-B2 | 4-carbonylamino-4-phenylpyrimidine compound or pharmaceutically acceptable salt thereof | GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2025-01-28 | — | — | US | disclosed |
| US-8211919-B2 | Amide derivatives as rock inhibitors | ASTELLAS PHARMA INC. (JP) | 2012-07-03 | — | — | US | disclosed |
| US-20090105231-A1 | AMIDE DERIVATIVES AS ROCK INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12208098-B2 | 4-carbonylamino-4-phenylpyrimidine compound or pharmaceutically acceptable salt thereof | SLC5A1, SLC10A1, DPP4 | SYK 2668/4885IKBKB 614/4885PAX8 3322/4885 |
| US-20090105231-A1 | AMIDE DERIVATIVES AS ROCK INHIBITORS | ROCK1, ROCK2, RHOA | SYK 891/4885IKBKB 489/4885PAX8 3961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.