Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620451 | 0.86 | MAPT (1.00) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3543325 | 0.85 | MAPT (0.71) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13755352 | 0.85 | MAPT (0.71) | MAPTKMT2AMEN1NPC1RAB9A | |
| Bicarbonate SCHEMBL3547040 | 0.82 | MAPT (0.71) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL4162969 | 0.82 | MAPT (0.75) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL13105213 | 0.81 | MAPT (0.73) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL197637 | 0.81 | MAPT (0.73) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL3539493 | 0.80 | MAPT (0.63) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL27022350 | 0.79 | MAPT (0.71) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL24590486 | 0.77 | MAPT (0.72) | MAPTKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215779-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215779-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | DGAT2, GPR119, DGAT1 | MAPT 2561/4885KMT2A 1599/4885MEN1 3117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.