Sugi Predict

Sugi Predict / Compounds / Hydrazine

Hydrazine

Hydrazine

SCHEMBL4517324

NN.c1ccc(CCc2ccccc2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 6/20 0.68
▸ MAOB P27338 6/20 0.68
▸ SMN1; SMN2 Q16637 2/20 0.67
▸ LOXL2 Q9Y4K0 2/20 0.67
▸ HTR2A P28223 2/20 0.67
▸ CYP2A6 P11509 1/20 0.67
▸ TAAR1 Q96RJ0 1/20 0.67
▸ ALDH1A1 P00352 2/20 0.61
▸ HPGD P15428 1/20 0.61
▸ ALOX15 P16050 1/20 0.61
▸ ALOX12 P18054 1/20 0.61
▸ CASP1 P29466 1/20 0.61
▸ HSD17B10 Q99714 1/20 0.61
▸ TDP1 Q9NUW8 2/20 0.58
▸ NPC1 O15118 1/20 0.57
▸ KDM1A O60341 1/20 0.57
▸ LMNA P02545 1/20 0.57
▸ CYP1A2 P05177 1/20 0.57
▸ CYP3A4 P08684 1/20 0.57
▸ HTR1A P08908 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL3440179 0.93 ALDH1A1 (0.69) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL9741303 0.93 ALDH1A1 (0.69) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL62125 0.93 ALDH1A1 (0.69) MAOAMAOBSMN1; SMN2LOXL2HTR2A
Hydroxyamine SCHEMBL2782141 0.90 MAOA (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A
Methylamine SCHEMBL3038332 0.90 MAOA (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL25402413 0.89 ALDH1A1 (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL11747668 0.89 ALDH1A1 (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL7899313 0.89 ALDH1A1 (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL1793454 0.89 ALDH1A1 (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A
SCHEMBL3759913 0.89 ALDH1A1 (0.65) MAOAMAOBSMN1; SMN2LOXL2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1040380-A Preparation is by the application as the precursor of ceramic product of the method for the poly-hydrogen silazane of hydrazine derivative and described silazane ATOCHEM (FR) 1990-03-14 — — CN claimed
EP-0351262-A1 Polysilazanes, their preparation and use as precursors for ceramic materials, and the ceramic materials ELF ATOCHEM S.A. (FR) 1990-01-17 — — EP claimed
CN-1038655-A Polysilazane, its preparation method, and use it for ceramic precursor and make described pottery ATOCHEM (FR) 1990-01-10 — — CN claimed
CN-110382453-A The manufacturing method of (methyl) acrylate 东亚合成株式会社 2019-10-25 — — CN disclosed
CN-110072507-A Cosmetic preparation fluorophor and cosmetic preparation 堺化学工业株式会社 2019-07-30 — — CN disclosed
CN-106456470-B Cosmetic material 堺化学工业株式会社 2019-07-16 — — CN disclosed
CN-105960379-B Hexagonal plate-like zinc oxide particles, method for producing same, cosmetic, filler, resin composition, infrared-reflective material, and coating composition 堺化学工业株式会社 2018-04-17 — — CN disclosed
CN-106456469-A Cosmetic 堺化学工业株式会社 2017-02-22 — — CN disclosed
CN-106456470-A Cosmetic material 堺化学工业株式会社 2017-02-22 — — CN disclosed
CN-106232089-A Skin care cosmetic 株式会社资生堂 2016-12-14 — — CN disclosed
CN-105960379-A Hexagonal plate-like zinc oxide particles, method for producing same, cosmetic, filler, resin composition, infrared-reflective material, and coating composition 堺化学工业株式会社 2016-09-21 — — CN disclosed
US-20060287308-A1 3-Aminoquinazolin-2,4-dione antibacterial agents ZOETIS WLC LLC 2006-12-21 — — US disclosed
US-7094780-B1 3-aminoquinazolin-2,4-dione antibacterial agents WARNER LAMBERT COMPANY LLC (US) 2006-08-22 — — US disclosed
US-20060183762-A1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS ZOETIS WLC LLC 2006-08-17 — — US disclosed
EP-1255739-A1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 2002-11-13 — — EP disclosed
WO-2001053273-A1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS WARNER-LAMBERT COMPANY (US) 2001-07-26 — — WO disclosed
CN-1040380-A Preparation is by the application as the precursor of ceramic product of the method for the poly-hydrogen silazane of hydrazine derivative and described silazane ATOCHEM (FR) 1990-03-14 — — CN disclosed
EP-0351262-A1 Polysilazanes, their preparation and use as precursors for ceramic materials, and the ceramic materials ELF ATOCHEM S.A. (FR) 1990-01-17 — — EP disclosed
CN-1038655-A Polysilazane, its preparation method, and use it for ceramic precursor and make described pottery ATOCHEM (FR) 1990-01-10 — — CN disclosed
US-4336085-A MODIFYING THE DETONATION VELOCITY WALKER FRANKLIN E 1982-06-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060183762-A1 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS ABL1, NQO2, CBR3 MAOA 2191/4885MAOB 1792/4885SMN1; SMN2 4374/4885
US-20060287308-A1 3-Aminoquinazolin-2,4-dione antibacterial agents ABL1, NQO2, AAAS MAOA 2193/4885MAOB 1781/4885SMN1; SMN2 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.