Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718866 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL14243000 | 0.81 | NPC1 (0.52) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL29588009 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL4535542 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL3719830 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL10915469 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL10654179 | 0.78 | MAPT (0.55) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL29588016 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL11512455 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1HTTPOLB | |
| SCHEMBL8756218 | 0.77 | HTT (0.58) | ALDH1A1MAPTL3MBTL1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | ALDH1A1 2449/4885MAPT 3649/4885GAA 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.