Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.36 |
| ▸ | TUBB | P07437 | 4/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3990468 | 0.88 | ALDH1A1 (0.50) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3984903 | 0.82 | MAPT (0.44) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL4523894 | 0.81 | ALDH1A1 (0.58) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3990474 | 0.76 | KDM4E (0.47) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL4523898 | 0.71 | MAPT (0.55) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL7856277 | 0.70 | KDM4E (0.77) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3993557 | 0.66 | EGFR (0.42) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3993561 | 0.66 | MAPT (0.48) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3986203 | 0.64 | ALDH1A1 (0.55) | ALDH1A1RAB9AKDM4EHPGDNPC1 | |
| SCHEMBL3987381 | 0.64 | ALDH1A1 (0.51) | ALDH1A1RAB9AKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090233979-A1 | Indole Derivatives and Their Use as Thyroid Receptor Ligands | KARO BIO AB (SE) | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233979-A1 | Indole Derivatives and Their Use as Thyroid Receptor Ligands | TSHR, TRHR, THRA | ALDH1A1 1439/4885RAB9A 2261/4885KDM4E 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.