SCHEMBL45192

SCHEMBL45192

COC(C)(C)c1cc(C(C)(C)OC)cc(C(C)(C)OC)c1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 3/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
MAPK1 P28482 1/20 0.33
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44978 0.91 GABRA1 (0.48) HSD17B10ALDH1A1GABRA1GABRB2ALOX15
SCHEMBL3262455 0.91 GABRA1 (0.48) HSD17B10ALDH1A1GABRA1GABRB2ALOX15
SCHEMBL23113609 0.87 HSD17B10 (0.41) HSD17B10ALDH1A1MAPK1
SCHEMBL44954 0.83 MAPK1 (0.44) HSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL15726942 0.83 GABRA1 (0.41) HSD17B10ALDH1A1GABRA1GABRB2
SCHEMBL10271927 0.83 CAMK1D (0.32) HSD17B10GABRA1GABRB2
SCHEMBL31511037 0.81 ALDH1A1 (0.55) ALDH1A1
SCHEMBL4191021 0.81 HSD17B10 (0.36) HSD17B10ALDH1A1MAPK1
SCHEMBL12077202 0.81 HSD17B10 (0.32) HSD17B10
SCHEMBL14994436 0.81 GABRA1 (0.39) HSD17B10GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 221 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795247-B2 Polyolefin dispersants and methods of making and using thereof THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-10-24 US claimed
US-20210189030-A1 Polyolefin Dispersants and Methods of Making and Using Thereof UNIVERSITY OF SOUTHERN MISSISSIPPI 2021-06-24 US claimed
EP-3684842-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF Chevron Oronite Company LLC (US) 2020-07-29 EP claimed
US-20190284314-A1 Polyolefin Dispersants and Methods of Making and Using Thereof CHEVRON ORONITE COMPANY LLC. 2019-09-19 US claimed
WO-2019055978-A1 POLYOLEFIN DISPERSANTS AND METHODS OF MAKING AND USING THEREOF CHEVRON ORONITE COMPANY LLC (US) 2019-03-21 WO claimed
EP-2387592-B1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIV OF SOUTHERN MISSISSIPPI (US) 2018-08-29 EP claimed
US-9650449-B2 Functionalization of polyolefins with phenoxy derivatives THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2017-05-16 US claimed
EP-2459599-B1 IN SITU FORMATION OF HYDROXY CHAIN END FUNCTIONAL POLYOLEFINS UNIV SOUTHERN MISSISSIPPI (US) 2016-07-20 EP claimed
US-20130281742-A1 METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES THE UNIVERSITY OF AKRON (US) 2013-10-24 US claimed
US-20130131280-A1 FUNCTIONALIZATION OF POLYOLEFINS WITH PHENOXY DERIVATIVES THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-05-23 US claimed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US claimed
EP-0609737-B1 Process for producing a halogenated butyl rubber BAYER INC (CA) 2000-06-07 EP claimed
US-5473029-A Copolymerization of isobutylene with a conjugated diolefin bearing an allylic halide in the presence of an initiator and a lewis acid BAYER RUBBER INC. (CA) 1995-12-05 US claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 EP claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
EP-0346919-A2 Improved thermoplastic elastomers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-12-20 EP claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281742-A1 METHOD AND SYNTHESIS OF INITIATORS FOR TELECHELIC POLYISOBUTYLENES TET1, TET3, DNMT1 HSD17B10 619/4885ALDH1A1 640/4885GABRA1 1294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.