Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519503 | 0.98 | ABCC9 (0.36) | NR1H4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL1573133 | 0.95 | ABCC9 (0.40) | NR1H4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4497581 | 0.83 | ABCC9 (0.41) | NR1H4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4502430 | 0.82 | NR1H4 (0.42) | NR1H4LPAR1KMT2A | |
| SCHEMBL1573154 | 0.75 | ABCC9 (0.45) | NR1H4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL4514601 | 0.69 | SMPD1 (0.38) | NR1H4POLBTP53MEN1KMT2A | |
| SCHEMBL4504643 | 0.68 | NR1H4 (0.40) | NR1H4AKR1C2AKR1C1MEN1KMT2A | |
| SCHEMBL4420899 | 0.68 | ABCC9 (0.47) | NR1H4ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL15903926 | 0.66 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8MEN1 | |
| SCHEMBL29440834 | 0.66 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9120819-B2 | FGF-receptor agonist dimeric compounds | SANOFI (FR) | 2015-09-01 | — | — | US | disclosed |
| US-20090069368-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | SANOFI-AVENTIS (FR) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069368-A1 | FGF-RECEPTOR AGONIST DIMERIC COMPOUNDS | FGF2, FGFR1, FGF1 | NR1H4 209/4885ABCC9 3947/4885ABCC8 3724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.