SCHEMBL45200

SCHEMBL45200

CC(Cl)Cc1ccc(CC(C)Cl)cc1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.48
SLC6A3 Q01959 2/20 0.48
TAAR1 Q96RJ0 5/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
SLC6A4 P31645 3/20 0.40
MAOA P21397 1/20 0.40
SIGMAR1 Q99720 1/20 0.40
CYP2A6 P11509 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2326795 0.89 SLC6A2 (0.64) SLC6A2SLC6A3TAAR1SLC6A4CYP2A6
SCHEMBL2325993 0.87 GFER (0.46) SLC6A2SLC6A3TAAR1MAOA
SCHEMBL27286900 0.87 TRPA1 (0.55) SLC6A2SLC6A3TAAR1MAOA
SCHEMBL9773345 0.87 TRPA1 (0.55) SLC6A2SLC6A3TAAR1MAOA
SCHEMBL2329406 0.87 TAAR1 (0.61) SLC6A2TAAR1ESR1ESR2
SCHEMBL66064 0.86 SIGMAR1 (0.58) SLC6A2SLC6A3TAAR1SLC6A4MAOA
SCHEMBL27878590 0.86 SIGMAR1 (0.58) SLC6A2SLC6A3TAAR1SLC6A4MAOA
SCHEMBL28585943 0.85 SLC6A4 (0.45) SLC6A2SLC6A3SLC6A4
Hydrochloric Acid SCHEMBL22207848 0.84 SIGMAR1 (0.56) SLC6A2SLC6A3TAAR1SLC6A4MAOA
Ammonia Solution, Strong SCHEMBL8142874 0.84 SIGMAR1 (0.56) SLC6A2SLC6A3TAAR1SLC6A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2284203-B1 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE CO (US) 2015-03-04 EP claimed
CN-102532368-B Rare earth catalyst and method for polymerizing conjugated diene by using same UNIV BEIJING CHEMICAL 2014-04-02 CN claimed
US-8575279-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-11-05 US claimed
US-20130150539-A1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-06-13 US claimed
US-8383736-B2 Method for preparation of polyolefins containing exo-olefin chain ends CHEVRON ORONITE COMPANY LLC (US) 2013-02-26 US claimed
US-8063154-B2 Preparation of exo-olefin terminated polyolefins via quenching with alkoxysilanes or ethers THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2011-11-22 US claimed
US-8013073-B2 Method for preparing polyolefins containing vinylidine end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE COMPANY LLC (US) 2011-09-06 US claimed
JP-4729040-B2 2011-07-20 JP claimed
EP-1781715-B1 METHOD FOR PREPARATION OF POLYOLEFINS CONTAINING EXO-OLEFIN CHAIN ENDS CHEVRON ORONITE CO (US) 2011-05-18 EP claimed
EP-2284203-A2 Method for preparation of polyolefins containing exo-olefin chain ends Chevron Oronite Company LLC (US) 2011-02-16 EP claimed
WO-2002050129-A1 PROCESS FOR POLYMERIZING CATIONICALLY POLYMERIZABLE MONOMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-06-27 WO claimed
WO-2001036498-A1 PRODUCTION OF ISOBUTYLENE COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 2001-05-25 WO claimed
EP-0609737-B1 Process for producing a halogenated butyl rubber BAYER INC (CA) 2000-06-07 EP claimed
US-5473029-A Copolymerization of isobutylene with a conjugated diolefin bearing an allylic halide in the presence of an initiator and a lewis acid BAYER RUBBER INC. (CA) 1995-12-05 US claimed
EP-0609737-A2 Process for producing a halogenated butyl rubber BAYER RUBBER INC. (CA) 1994-08-10 EP claimed
US-RE34640-E Polymerizing isobutylene, adding monomer to make block polymer; metal halide, initiator and electron pair doner solvent UNIVERSITY OF AKRON (US) 1994-06-14 US claimed
EP-0341012-B1 UNIFORM MOLECULAR WEIGHT POLYMERS EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1992-12-30 EP claimed
WO-1991011468-A1 NEW THERMOPLASTIC ELASTOMERS THE UNIVERSITY OF AKRON (US) 1991-08-08 WO claimed
US-4946899-A CARBOCATIONIC POLYMERIZATION INVOLVING HOMOPOLYMERIZATION OF ELASTOMER FOLLOWED BY COPOLYMERIZATION TO ADD GLASSY SEGMENTS; FORMING LIVING POLYMERS WITH A METAL HALIDE, PROMOTER AND SOLVENT MIXTURE THE UNIVERSITY OF AKRON (US) 1990-08-07 US claimed
EP-0341012-A2 Uniform molecular weight polymers EDISON POLYMER INNOVATION CORPORATION ( EPIC) (US) 1989-11-08 EP claimed