SCHEMBL66064

SCHEMBL66064

CC(Cl)Cc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.58
TAAR1 Q96RJ0 5/20 0.58
SLC6A2 P23975 3/20 0.58
SLC6A4 P31645 2/20 0.58
SLC6A3 Q01959 2/20 0.58
MAOA P21397 1/20 0.58
CYP2A6 P11509 1/20 0.58
ADORA2A P29274 1/20 0.58
ADORA1 P30542 1/20 0.58
SLC18A2 Q05940 1/20 0.54
CYP2D6 P10635 1/20 0.54
TRPA1 O75762 2/20 0.52
EPHX1 P07099 1/20 0.50
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
HTR2A P28223 1/20 0.48
ADRA1A P35348 1/20 0.48
OPRK1 P41145 1/20 0.48
KCNH2 Q12809 1/20 0.48
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27878590 1.00 SIGMAR1 (0.58) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Hydrochloric Acid SCHEMBL22207848 0.97 SIGMAR1 (0.56) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Ammonia Solution, Strong SCHEMBL8142874 0.97 SIGMAR1 (0.56) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL45200 0.86 SLC6A2 (0.48) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL45023 0.82 PNMT (0.52) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL9239627 0.81 SIGMAR1 (0.50) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL11602141 0.81 LTA4H (0.58) SIGMAR1SLC6A2SLC6A3MAOA
SCHEMBL252017 0.78 EPHX1 (0.55) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
Isobutylbenzene SCHEMBL2571645 0.78 SIGMAR1 (0.64) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL4785594 0.78 SIGMAR1 (0.64) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117624688-A Preparation method of film for photovoltaic capacitor 浙江南洋华诚科技有限公司 2024-03-01 CN claimed
CN-114621709-A High-water-resistance bio-based formaldehyde-free setting agent special for mineral wool 江苏艾科赛特新材料有限公司 2022-06-14 CN claimed
CN-112608402-B Styrene block copolymer and preparation method thereof 北京化工大学 2022-02-11 CN claimed
CN-112608402-A Styrene block copolymer and preparation method thereof 北京化工大学 2021-04-06 CN claimed
WO-2020145347-A1 PRODUCTION METHOD FOR α-CHLOROETHYL BENZYL CHLORIDE AND PRODUCTION METHOD FOR CHLOROMETHYLSTYRENE 長瀬産業株式会社 2020-07-16 WO claimed
CN-111094394-A Polyolefin dispersants and methods of making and using the same 雪佛龙奥伦耐有限责任公司 2020-05-01 CN claimed
US-9812661-B2 Organic electroluminescent device IDEMITSU KOSAN CO., LTD. (JP) 2017-11-07 US claimed
US-9716235-B2 9,10-bis[2-(p-substituted phenyl)pyrimidin-4-yl] anthracene compounds, methods of preparing the same, organic electroluminescent devices and organic electroluminescent display apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2017-07-25 US claimed
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus BOE TECHNOLOGY GROUP CO., LTD. (CN) 2015-07-30 US claimed
EP-2314558-B1 BENZOFLUORANTHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE ELEMENT COMPRISING SAME IDEMITSU KOSAN CO (JP) 2014-05-14 EP claimed
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-02-10 US claimed
EP-1803751-B1 Method for preparing polyolefins containing vinylidene end groups using polymeric nitrogen compounds CHEVRON ORONITE CO (US) 2010-06-30 EP claimed
EP-1803748-B1 Method for preparing polyolefins containing vinylidene end groups using nonaromatic heterocyclic compounds CHEVRON ORONITE CO (US) 2010-06-09 EP claimed
CN-100482700-C Splitblip molecular weight distribution high-cis-polydiene and preparation method thereof UNIV BEIJING CHEMICAL (CN) 2009-04-29 CN claimed
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY OF CHINESE ACADEMY OF SCIENCES (CN) 2009-04-23 US claimed
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS IDEMITSU KOSAN CO., LTD. (JP) 2009-02-12 US claimed
CN-100448898-C Rare-earth catalyst and conjugated diene polymerization process CHINA PETROLEUM & CHEMICAL (CN) 2009-01-07 CN claimed
CN-101085818-A Splitblip molecular weight distribution high-cis-polydiene and preparation method thereof UNIV BEIJING CHEMICAL (CN) 2007-12-12 CN claimed
CN-1840552-A Rare-earth catalyst and conjugated diene polymerization process CHINA PETROLEUM & CHEMICAL (CN) 2006-10-04 CN claimed
EP-0065692-B1 DERIVATIVES OF ERYTHRO-1,2,3-TRIPHENYL-1-PENTANONE, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINES Klinge Pharma GmbH (DE) 1984-12-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, EML4 SIGMAR1 2177/4885TAAR1 707/4885SLC6A2 197/4885
US-20090102356-A1 NOVEL ORGANIC COMPOUND HAVING ELECTRON-TRANSPORTING AND/OR HOLE-BLOCKING PERFORMANCE AND ITS USE AND OLEDs COMPRISING THE COMPOUND SLCO4C1, SLCO1B1, SLCO2B1 SIGMAR1 1899/4885TAAR1 2676/4885SLC6A2 423/4885
US-20090043116-A1 HETERO-POLYCYCLIC COMPOUNDS, AND COLORING MATTERS, PIGMENTS, DYES, COLOR-CHANGING MATERIAL COMPOSITIONS, AND COLOR-CHANGING FILMS, MADE BY USING THE COMPOUNDS PBRM1, BICRA, PARG SIGMAR1 3313/4885TAAR1 3031/4885SLC6A2 2445/4885
US-20150214487-A1 9,10-Bis[2-(p-substituted phenyl)pyrimidin-4-yl] Anthracene Compounds, Methods of Preparing the Same, Organic Electroluminescent Devices and Organic Electroluminescent Display Apparatus P2RY10, P2RY4, APRT SIGMAR1 4120/4885TAAR1 2837/4885SLC6A2 949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.