Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NQO1 | P15559 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522124 | 0.90 | NQO1 (0.37) | MAPTKDM4ERAB9ANQO1PADI4 | |
| SCHEMBL3495642 | 0.86 | PADI4 (0.35) | MAPTKDM4ERAB9APADI4FEN1 | |
| SCHEMBL4520046 | 0.78 | GAA (0.40) | MAPTKDM4ERAB9AKMT2AMEN1 | |
| SCHEMBL4527553 | 0.74 | BCHE (0.44) | KDM4ENQO1ALDH1A1LMNAABCG2 | |
| SCHEMBL4510109 | 0.74 | CYSLTR2 (0.44) | NQO1CYP1A2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4527547 | 0.74 | BCHE (0.44) | KDM4ENQO1ALDH1A1LMNAABCG2 | |
| SCHEMBL4510106 | 0.74 | CYSLTR2 (0.44) | NQO1CYP1A2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL4520684 | 0.73 | NQO1 (0.42) | KDM4ENQO1PADI4CYP1A2ALDH1A1 | |
| SCHEMBL4520585 | 0.73 | NQO1 (0.42) | KDM4ENQO1PADI4CYP1A2ALDH1A1 | |
| SCHEMBL4520592 | 0.73 | NQO1 (0.42) | KDM4ENQO1PADI4CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | COL2A1, COL1A1, SMAD2 | MAPT 3377/4885KDM4E 1537/4885RAB9A 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.