Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520824 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1ABCG2NR1H4APP | |
| SCHEMBL2283102 | 0.84 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1ABCG2APPMAOB | |
| SCHEMBL2283107 | 0.84 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1ABCG2APPMAOB | |
| SCHEMBL2276772 | 0.84 | ABCG2 (0.47) | CYSLTR2CYSLTR1ABCG2NR1H4APP | |
| SCHEMBL2276769 | 0.84 | ABCG2 (0.47) | CYSLTR2CYSLTR1ABCG2NR1H4APP | |
| SCHEMBL2277984 | 0.83 | ABCG2 (0.49) | CYSLTR2CYSLTR1ABCG2APPMAOB | |
| SCHEMBL2277980 | 0.83 | ABCG2 (0.49) | CYSLTR2CYSLTR1ABCG2APPMAOB | |
| SCHEMBL4510787 | 0.82 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ABCG2NR1H4APP | |
| SCHEMBL4510789 | 0.82 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1ABCG2NR1H4APP | |
| SCHEMBL2274827 | 0.80 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1ABCG2MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-04 | — | — | US | disclosed |
| EP-1857104-A1 | USE OF CINNAMOYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143368-A1 | Use of Cinnamoyl Compound | COL2A1, COL1A1, SMAD2 | CYSLTR2 1079/4885CYSLTR1 1024/4885ABCG2 1660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.