SCHEMBL452098

SCHEMBL452098

NCCOCCOCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25006051 1.00
SCHEMBL25113460 1.00
SCHEMBL20233856 1.00
SCHEMBL999402 0.95
SCHEMBL1263364 0.92
SCHEMBL2422200 0.86 ALDH1A1 (0.32)
SCHEMBL21765789 0.85 ADRB2 (0.31)
SCHEMBL10447832 0.85 ODC1 (0.36)
SCHEMBL25602000 0.85 ODC1 (0.36)
SCHEMBL17167688 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118021978-A GHRH antagonists for use in methods of treating sarcoidosis 迈阿密大学 2024-05-14 CN claimed
EP-4331674-A2 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2024-03-06 EP claimed
US-11851468-B2 Treatment of neurological diseases UNIVERSITY OF LANCASTER (GB) 2023-12-26 US claimed
US-20230287051-A1 INHIBITORS OF COMPLEMENT FACTOR C3 AND THEIR MEDICAL USES ZEALAND PHARMA A/S (DK) 2023-09-14 US claimed
EP-3999095-B1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS UNIV MIAMI (US) 2023-09-13 EP claimed
CN-116209671-A Inhibitors of complement factor C3 and medical uses thereof 西兰制药第三特殊目的公司 2023-06-02 CN claimed
EP-4182023-A1 INHIBITORS OF COMPLEMENT FACTOR C3 AND THEIR MEDICAL USES ZP SPV 3 K/S (DK) 2023-05-24 EP claimed
US-11382956-B2 Amylin analogues ZEALAND PHARMA A/S (DK) 2022-07-12 US claimed
EP-3999095-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2022-05-25 EP claimed
US-20220143149-A1 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2022-05-12 US claimed
EP-1718665-A4 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS INC (US) 2008-05-14 EP claimed
WO-2008021560-A2 DPP-IV RESISTANT GIP HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2008-02-21 WO claimed
EP-1853627-A2 GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES Amylin Pharmaceuticals, Inc. (US) 2007-11-14 EP claimed
JP-2007525495-A 2007-09-06 JP claimed
WO-2007022123-A2 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2007-02-22 WO claimed
US-20060293232-A1 Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS, INC. (US) 2006-12-28 US claimed
EP-1718665-A2 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES Amylin Pharmaceuticals, Inc. (US) 2006-11-08 EP claimed
WO-2006086769-A2 GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2006-08-17 WO claimed
US-20060094652-A1 Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS, INC. 2006-05-04 US claimed
WO-2005077072-A2 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2005-08-25 WO claimed