Acetic Acid

Acetic Acid

SCHEMBL4521

C=C1C[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]2(C)[C@@]1(O)C(C)=O.CC(=O)O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.70
MEN1 O00255 3/20 0.70
KMT2A Q03164 3/20 0.70
TDP1 Q9NUW8 1/20 0.70
PGR P06401 3/20 0.68
AR P10275 3/20 0.68
CHRM1 P11229 2/20 0.68
SMN1; SMN2 Q16637 4/20 0.61
NR3C1 P04150 3/20 0.61
CYP2C9 P11712 2/20 0.61
HIF1A Q16665 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
CYP3A4 P08684 2/20 0.61
MAPK1 P28482 2/20 0.61
ABCB11 O95342 1/20 0.61
POLB P06746 1/20 0.61
CYP19A1 P11511 8/20 0.56
FNTA P49354 1/20 0.56
FNTB P49356 1/20 0.56
ADORA3 P0DMS8 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1650395 0.98 LMNA (0.72) LMNAMEN1KMT2ATDP1PGR
SCHEMBL10868391 0.98 LMNA (0.72) LMNAMEN1KMT2ATDP1PGR
SCHEMBL144436 0.98 LMNA (0.72) LMNAMEN1KMT2ATDP1PGR
SCHEMBL8859777 0.92 LMNA (0.67) LMNAMEN1KMT2ATDP1PGR
Megestrol Acetate SCHEMBL5599601 0.88 AR (0.81) LMNAMEN1KMT2ATDP1PGR
SCHEMBL11512435 0.87 FNTA (0.73) LMNAMEN1KMT2ATDP1PGR
SCHEMBL11513690 0.87 LMNA (0.58) LMNAMEN1KMT2ATDP1PGR
SCHEMBL11513687 0.87 LMNA (0.58) LMNAMEN1KMT2ATDP1PGR
Acetic Acid SCHEMBL25192781 0.83 PGR (0.96) LMNAMEN1KMT2ATDP1PGR
Acetic Acid SCHEMBL28104035 0.82 PGR (0.94) LMNAMEN1KMT2ATDP1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11290 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
EP-4647069-A1 DRUGS AND COMPOSITIONS FOR USE IN THE TREATMENT OF RETT SYNDROME UNIVERSITA' DEGLI STUDI DI TRIESTE (IT) 2025-11-12 EP claimed
WO-2025151711-A1 NUCLEIC ACID VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
WO-2025151713-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS Arkea Bio Corp. (US) 2025-07-17 WO claimed
US-20250222082-A1 PROTEIN AND PEPTIDE VACCINES TARGETING METHANOGENS ARKEA BIO CORP (US) 2025-07-10 US claimed
WO-2025128700-A1 CELL-BASED VACCINES Arkea Bio Corp. (US) 2025-06-19 WO claimed
WO-2025085377-A1 USE OF ZOALENE IN LIVESTOCK ZOETIS SERVICES LLC (US) 2025-04-24 WO claimed
EP-4524131-A1 SMALL MOLECULES FOR TREATING CANCER, INHABITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH AlonBio Ltd. (IL) 2025-03-19 EP claimed
CN-116217648-B Preparation and purification method of melengestrol acetate 湖南科益新生物医药有限公司 2025-01-28 CN claimed
US-5227167-A LONG-TERM DELIVERY DEVICE INCLUDING HYDROPHOBIC LOADING DOSE ALZA CORPORATION (US) 1993-07-13 US claimed
WO-1992022346-A1 LONG-TERM DELIVERY DEVICE INCLUDING HYDROPHOBIC LOADING DOSE ALZA CORPORATION (US) 1992-12-23 WO claimed
EP-0510062-A1 LONG-TERM DELIVERY DEVICE INCLUDING LOADING DOSE. ALZA CORP (US) 1992-10-28 EP claimed
EP-0491803-A1 IMPLANTABLE DELIVERY DISPENSER. ALZA CORP (US) 1992-07-01 EP claimed
US-5112614-A IMPLANTABLE DELIVERY DISPENSER ALZA CORPORATION (US) 1992-05-12 US claimed
EP-0463454-A2 Transdermal administration to humans and animals DERMAMED (IL) 1992-01-02 EP claimed
WO-1991010423-A1 LONG-TERM DELIVERY DEVICE INCLUDING LOADING DOSE ALZA CORPORATION (US) 1991-07-25 WO claimed
WO-1991004016-A1 IMPLANTABLE DELIVERY DISPENSER ALZA CORPORATION (US) 1991-04-04 WO claimed
EP-0179496-A1 16-Sulfinylmethyl-steroids, their preparation and use THE UPJOHN COMPANY (US) 1986-04-30 EP claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed