Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526559 | 0.91 | BIRC5 (0.47) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL4531880 | 0.87 | CYP1A2 (0.42) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL4529286 | 0.87 | NPC1 (0.42) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL4522982 | 0.87 | LMNA (0.50) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL4527844 | 0.86 | TDP2 (0.41) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL15910585 | 0.86 | LMNA (0.43) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL15910479 | 0.86 | LMNA (0.43) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL4533531 | 0.80 | CYP1A2 (0.42) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL4521246 | 0.80 | AKR1C3 (0.44) | BIRC5NR2F2TDP2LMNAALDH1A1 | |
| SCHEMBL20300703 | 0.80 | LMNA (0.39) | TDP2LMNAALDH1A1PDE4BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736471-B1 | 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES | MITSUI CHEMICALS AGRO INC (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-7632783-B2 | fungicides, pesticides for protecting rice crop, tomatoes, cucumbers and green beans; 3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline | MITSUI CHEMICALS AGRO, INC. (JP) | 2009-12-15 | — | — | US | disclosed |
| CN-100556904-C | 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds | SANKYO AGRO CO LTD (JP) | 2009-11-04 | — | — | CN | disclosed |
| US-20080275242-A1 | 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound | MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) | 2008-11-06 | — | — | US | disclosed |
| CN-1910172-A | 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds | SANKYO AGRO CO LTD (JP) | 2007-02-07 | — | — | CN | disclosed |
| EP-1736471-A1 | 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES | Sankyo Agro Company, Limited (JP) | 2006-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275242-A1 | 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound | QTRT1, RABL3, RECQL | BIRC5 435/4885NR2F2 2146/4885TDP2 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.