Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4523968 | 0.73 | POLB (0.43) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL7158988 | 0.69 | PSIP1 (0.50) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14272117 | 0.67 | PSIP1 (0.48) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14491150 | 0.67 | HTR6 (0.50) | SMN1; SMN2RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL3483640 | 0.66 | PSIP1 (0.47) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL11922695 | 0.65 | PSIP1 (0.61) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10749372 | 0.65 | CYP19A1 (0.58) | POLBSMN1; SMN2ALDH1A1MPOMAPT | |
| SCHEMBL24625403 | 0.64 | PSIP1 (0.54) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3147023 | 0.64 | PSIP1 (0.48) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL1283787 | 0.64 | PSIP1 (0.48) | POLBSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2124919-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008103314-A2 | METHODS FOR MODULATING BONE FORMATION AND MINERALIZATION | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-08-28 | — | — | WO | disclosed |