SCHEMBL3483640

SCHEMBL3483640

O=S(=O)(Cc1ccccc1SSc1ccccc1CS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.47
APOBEC3G Q9HC16 1/20 0.45
MAPT P10636 1/20 0.42
MPO P05164 1/20 0.41
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 4/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
HTR6 P50406 1/20 0.38
HSD11B1 P28845 3/20 0.38
POLB P06746 2/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3483641 0.85 PSIP1 (0.44) PSIP1MAPTMPOTSHRHSD17B10
SCHEMBL945221 0.81 PSIP1 (0.44) PSIP1APOBEC3GMAPTSMN1; SMN2NPC1
SCHEMBL11922695 0.76 PSIP1 (0.61) PSIP1APOBEC3GMAPTMPOTSHR
SCHEMBL943394 0.76 APOBEC3G (0.48) APOBEC3GMAPTLMNAPOLBKMT2A
SCHEMBL1283787 0.74 PSIP1 (0.48) PSIP1MAPTTSHRHSD17B10SMN1; SMN2
SCHEMBL1714597 0.74 PSIP1 (0.48) PSIP1MAPTMPOTSHRHSD17B10
SCHEMBL2808506 0.74 PSIP1 (0.54) PSIP1APOBEC3GMAPTHSD17B10SMN1; SMN2
SCHEMBL3147023 0.74 PSIP1 (0.48) PSIP1MAPTMPOTSHRHSD17B10
SCHEMBL4067607 0.74 PSIP1 (0.48) PSIP1MAPTMPOTSHRHSD17B10
SCHEMBL14272117 0.74 PSIP1 (0.48) PSIP1MAPTTSHRHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110306798-A1 Methods for Producing Arylsulfur Pentafluorides UBE INDUSTRIES, LTD. (JP) 2011-12-15 US disclosed
US-7851646-B2 formed by reacting aryl sulfur compound with halogen and fluoro salt to form arylsulfur halotetrafluoride which is reacted with fluoride source to form target arylsulfur pentafluoride; for production of fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-12-14 US disclosed
US-7820864-B2 2,3,4,5,6-pentafluorophenylsulfur pentafluoride; as intermediates for introduce sulfur pentafluoride groups into various commercial organic molecules; liquid crystals, fungicides, herbicides, and insecticides IM&T RESEARCH, INC. (US) 2010-10-26 US disclosed
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-03-25 US disclosed
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2010-02-04 US disclosed
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides IM&T RESEARCH, INC. (US) 2009-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090287024-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA PSIP1 313/4885APOBEC3G 1330/4885MAPT 3764/4885
US-20100076215-A9 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA PSIP1 313/4885APOBEC3G 1330/4885MAPT 3764/4885
US-20100029992-A1 Process for Producing Arylsulfur Pentafluorides PFAS, MPST, ARSA PSIP1 313/4885APOBEC3G 1330/4885MAPT 3764/4885
US-20110306798-A1 Methods for Producing Arylsulfur Pentafluorides PFAS, ARSA, HDHD5 PSIP1 267/4885APOBEC3G 860/4885MAPT 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.