Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811435 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL8311603 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL9486743 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL8311599 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL7811433 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL1686983 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL22582139 | 0.96 | USP2 (0.31) | USP2ESR1KDM4E | |
| SCHEMBL16673765 | 0.77 | — | — | |
| SCHEMBL19486294 | 0.74 | — | — | |
| SCHEMBL9470709 | 0.74 | USP2 (0.37) | USP2ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372248-B | Preparation method of anti-mud agent suitable for high-mud-content concrete | 北京工业大学 | 2021-08-13 | — | — | CN | claimed |
| CN-109761871-B | Synthetic method of aztreonam monocyclic parent nucleus | 山东昌邑四方医药化工有限公司 | 2020-11-24 | — | — | CN | claimed |
| US-7601832-B2 | combining [3S]3-amino-4-methyl-2-oxo-1-azetidinesulfonic acid with TAEM to obtain [3S-[3 alpha (Z),4 beta ]]-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid; one pot processs; antibiotic | SICOR, INC. (US) | 2009-10-13 | — | — | US | claimed |
| CN-110372248-B | Preparation method of anti-mud agent suitable for high-mud-content concrete | 北京工业大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-110372248-B | Preparation method of anti-mud agent suitable for high-mud-content concrete | 北京工业大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-109761871-B | Synthetic method of aztreonam monocyclic parent nucleus | 山东昌邑四方医药化工有限公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-100586930-C | Preparation method of aztreonam intermediate (3S-trans)-3-amido-4-methyl-2-oxo-1-sulfoazetidine | CHONGQING LUMMY PHARMACEUTICAL | 2010-02-03 | — | — | CN | disclosed |
| US-7601832-B2 | combining [3S]3-amino-4-methyl-2-oxo-1-azetidinesulfonic acid with TAEM to obtain [3S-[3 alpha (Z),4 beta ]]-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid; one pot processs; antibiotic | SICOR, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-7601832-B2 | combining [3S]3-amino-4-methyl-2-oxo-1-azetidinesulfonic acid with TAEM to obtain [3S-[3 alpha (Z),4 beta ]]-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-4-methyl-2-oxo-1-azetidinesulfonic acid; one pot processs; antibiotic | SICOR, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| CN-101362713-A | Preparation method of (3S-trans)-3-amido-4-methyl-2-oxo-1-sulfoazetidine | CHONGQING LUMMY PHARMACEUTICAL (CN) | 2009-02-11 | — | — | CN | disclosed |
| US-6916803-B2 | 3-(Heteroaryl acetamido)-2-oxo-azetidine-1-sulfonic acids derivatives as antibacterial agents | PANTHERIX, LTD. (GB) | 2005-07-12 | — | — | US | disclosed |
| US-4596777-A | Process for preparing (3S)-3-[[[2-(protected or unprotected amino)-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0086556-B1 | PROCESS FOR PREPARING (3S)-3-(((2-AMINO-4-THIAZOLYL)((1-CARBOXY-1-METHYLETHOXY)IMINO)-ACETYL)AMINO)-2-OXO-1-AZETIDINESULFONIC ACID AND 4-SUBSTITUTED DERIVATIVES | E.R. Squibb & Sons, Inc. (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4529698-A | Culturing Chromobacterium | E. R. SQUIBB & SONS, INC. (US) | 1985-07-16 | — | — | US | disclosed |
| US-4483797-A | (S)-3-Isocyanato-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1984-11-20 | — | — | US | disclosed |
| US-4443374-A | Process for preparing (3S)-3-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]-acetyl]amino]-2-oxo-1-azetidinesulfonic acid, and 4-substituted derivatives | E. R. SQUIBB & SONS, INC. (US) | 1984-04-17 | — | — | US | disclosed |
| EP-0097352-A2 | Process for the preparation of azetidine sulfonic acids | E.R. Squibb & Sons, Inc. (US) | 1984-01-04 | — | — | EP | disclosed |
| EP-0086556-A1 | Process for preparing (3S)-3-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)-acetyl)amino)-2-oxo-1-azetidinesulfonic acid and 4-substituted derivatives | E.R. Squibb & Sons, Inc. (US) | 1983-08-24 | — | — | EP | disclosed |
| US-4386034-A | Sulfamated amino acid amides | E. R. SQUIBB & SONS, INC. (US) | 1983-05-31 | — | — | US | disclosed |
| EP-0048953-A2 | Beta-lactam antibiotics | E.R. Squibb & Sons, Inc. (US) | 1982-04-07 | — | — | EP | disclosed |