Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811435 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL8311603 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL4523110 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL8311599 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL7811433 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL1686983 | 1.00 | FAP (0.30) | FAPUSP2ESR1AADATKDM4E | |
| SCHEMBL22582139 | 0.96 | USP2 (0.31) | USP2ESR1KDM4E | |
| SCHEMBL16673765 | 0.77 | — | — | |
| SCHEMBL19486294 | 0.74 | — | — | |
| SCHEMBL9470709 | 0.74 | USP2 (0.37) | USP2ESR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3676247-A1 | AZTREONAM DERIVATIVES AND USES THEREOF | Arixa Pharmaceuticals, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019070595-A1 | AZTREONAM DERIVATIVES AND USES THEREOF | ARIXA PHARMACEUTICALS, INC. (US) | 2019-04-11 | — | — | WO | disclosed |
| CN-100486964-C | Process of synthesizing (2S-trans)-3-methyl-4-oxo-1-azacyclo butyl sulfonic acid | BEIJING SECOND PHARMACEUTICAL (CN) | 2009-05-13 | — | — | CN | disclosed |
| CN-1974551-A | Process of synthesizing (2S-trans)-3-methyl-4-oxo-1-azacyclo butyl sulfonic acid | BEIJING SAIKE PHARMACEUTICAL I (CN) | 2007-06-06 | — | — | CN | disclosed |
| US-5194604-A | PROCESS AND INTERMEDIATES FOR BETA-LACTAMS HAVING AMINOTHIAZOLE(IMINOOXYACETIC ACID)ACETIC ACID SIDECHAINS | E. R. SQUIBB & SONS, INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0464705-A1 | Process and intermediates for Beta-lactams having aminothiazole (iminooxyacetic acid)acetic acid sidechains | E.R. SQUIBB & SONS, INC. (US) | 1992-01-08 | — | — | EP | disclosed |