Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077999 | 0.82 | TSHR (0.45) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30961 | 0.80 | TSHR (0.43) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL7170680 | 0.80 | TSHR (0.43) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30285352 | 0.80 | TSHR (0.43) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL9047033 | 0.80 | ALOX15 (0.48) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL4952777 | 0.80 | TSHR (0.56) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL8003440 | 0.78 | ALDH1A1 (0.45) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL5140971 | 0.78 | TSHR (0.42) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30285305 | 0.77 | TSHR (0.41) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL4565106 | 0.77 | TSHR (0.41) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 590 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630818-A | Protein-macromolecule conjugates and methods of use thereof | 北京轩义医药科技有限公司 | 2022-06-14 | — | — | CN | claimed |
| EP-3105367-B1 | PRIMARY AMINE-CONTAINING POLYMERS USEFUL AS SCALE INHIBITORS | CYTEC IND INC (US) | 2020-11-04 | — | — | EP | claimed |
| WO-2020162629-A1 | PATCH | 株式会社メディカルフロント | 2020-08-13 | — | — | WO | claimed |
| US-10646505-B2 | DNA-functionalized scaffolds for drug capture applications | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-05-12 | — | — | US | claimed |
| EP-2496987-B1 | A SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING | ALCON INC (CH) | 2020-04-29 | — | — | EP | claimed |
| EP-2625216-B1 | POLYMERISABLE CHAIN-EXTENDED POLYSILOXANES WITH PENDANT HYDROPHILIC GROUPS | NOVARTIS AG (CH) | 2019-06-05 | — | — | EP | claimed |
| CN-109310981-A | Composite material, its preparation and gas purification purposes | 南洋理工大学 | 2019-02-05 | — | — | CN | claimed |
| EP-3068814-B1 | AQUEOUS DISPERSION OF POLYMER MADE FROM MULTISTRUCTURED PARTICLES FOR AQUEOUS COATINGS HAVING IMPROVED BLOCKING AND FINGERPRINT RESISTANCE AND HARDNESS | ARKEMA FRANCE (FR) | 2018-08-08 | — | — | EP | claimed |
| US-10035923-B2 | Aqueous dispersion of polymer made from multistructured particles for aqueous coatings having improved blocking and fingerprint resistance and hardness | ARKEMA FRANCE (FR) | 2018-07-31 | — | — | US | claimed |
| EP-2625217-B1 | CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS | NOVARTIS AG (CH) | 2018-07-04 | — | — | EP | claimed |
| EP-0661320-A1 | Aqueous coating and its use in coating substrates | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1995-07-05 | — | — | EP | claimed |
| EP-0465302-B1 | Precursors of isocyanurate polymers having hydroxyl, urethane, isocyanate or acrylate groups, and process for their preparation | ATOCHEM ELF SA (FR) | 1994-12-28 | — | — | EP | claimed |
| EP-0430769-B1 | Application of antiadherent polyester composite films as supports for the fabrication of at least one layer of polyurethane utilisable in safety glasses | SAINT GOBAIN VITRAGE (FR) | 1994-07-13 | — | — | EP | claimed |
| EP-0419615-B1 | COMPOSITE POLYESTER FILMS AS FINAL COATING SUPPORTS | RHONE-POULENC FILMS (FR) | 1993-09-29 | — | — | EP | claimed |
| US-5141783-A | Using a support film of semicrystalline polyester having coatings of fluoropolymer and a sulfo-containing polyester | SAINT-GOBAIN VITRAGE INTERNATIONAL C/O SAINT-GOBAIN RECHERCHE (FR) | 1992-08-25 | — | — | US | claimed |
| US-5128206-A | Magnetic recording supports | RHONE-POULENC CHIMIE (FR) | 1992-07-07 | — | — | US | claimed |
| EP-0465302-A1 | Precursors of isocyanurate polymers having hydroxyl, urethane, isocyanate or acrylate groups, and process for their preparation | ELF ATOCHEM S.A. (FR) | 1992-01-08 | — | — | EP | claimed |
| EP-0378954-A2 | Composite polyester films useful as magnetic recording carriers, and magnetic recording materials | RHONE-POULENC FILMS (FR) | 1990-07-25 | — | — | EP | claimed |
| US-4101461-A | Method for preparation of anion exchangers by substitution of hydrophilic polymeric gels | CZECHOSLOVENSKA AKADEMIE VED (CS) | 1978-07-18 | — | — | US | claimed |
| US-3991018-A | Method for preparation of cation exchangers by substitution of hydrophilic polymeric gels of crosslinked hydroxyalkyl acrylates and hydroxyalkylacrylamides | CESKOSLOVENSKA AKADEMIE VED (CS) | 1976-11-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10646505-B2 | DNA-functionalized scaffolds for drug capture applications | TOP1, TOP2A, DNA2 | TSHR 3282/4885SMN1; SMN2 1336/4885MAPT 1309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.