Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1077999 | 0.84 | TSHR (0.45) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30285352 | 0.83 | TSHR (0.43) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL45240 | 0.80 | TSHR (0.45) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL30961 | 0.78 | TSHR (0.43) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL9047033 | 0.78 | ALOX15 (0.48) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL4952777 | 0.78 | TSHR (0.56) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL5708695 | 0.77 | — | — | |
| SCHEMBL5140971 | 0.77 | TSHR (0.42) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL8003440 | 0.77 | ALDH1A1 (0.45) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 | |
| Acrylamide SCHEMBL28226782 | 0.76 | ALDH1A1 (0.41) | TSHRSMN1; SMN2MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | claimed |
| US-6503689-B2 | Crosslinked polymeric particles including one or more chromophore units such as anthracenyl methacrylate; relief images | SHIPLEY COMPANY, L.L.C. | 2003-01-07 | — | — | US | disclosed |
| US-6268467-B1 | Hydroxy or amino terminated hydrophilic polymers | BAUSCH & LOMB INCORPORATED | 2001-07-31 | — | — | US | disclosed |
| EP-0611367-B1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION | BAUSCH & LOMB (US) | 1997-06-25 | — | — | EP | disclosed |
| US-5512205-A | BIOMEDICAL ARTICLES, CONTACT LENSES | BAUSCH & LOMB INCORPORATED (US) | 1996-04-30 | — | — | US | disclosed |
| US-5449729-A | Vinyl monomer and crosslinking agent and acrylates with styrene | BAUSCH & LOMB INCORPORATED (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0611367-A1 | NOVEL UV CURABLE CROSSLINKING AGENTS USEFUL IN COPOLYMERIZATION. | BAUSCH & LOMB (US) | 1994-08-24 | — | — | EP | disclosed |
| US-5310779-A | Compatible crosslinkers having vinyl-, acrylic-and/or styrenyl-groups to crosslink incompatible unsaturated addition monomers; contact lens; molding materials | BAUSCH & LOMB INCORPORATED (US) | 1994-05-10 | — | — | US | disclosed |