Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509956 | 0.96 | PDCD1 (0.41) | ADORA1PDCD1CD274CYP1A2CYP3A4 | |
| SCHEMBL4525266 | 0.90 | CD274 (0.48) | PDCD1CD274MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4514401 | 0.87 | CHRM2 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19LMNA | |
| SCHEMBL4516325 | 0.83 | VSIR (0.40) | ADORA1PDCD1CD274 | |
| SCHEMBL4512711 | 0.79 | PRMT5 (0.41) | PDCD1CD274CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4517460 | 0.77 | VSIR (0.45) | PDCD1CD274 | |
| SCHEMBL4525368 | 0.77 | CD274 (0.36) | PDCD1CD274CYP3A4LMNAMEN1 | |
| SCHEMBL2511037 | 0.76 | FYN (0.39) | CYP1A2CYP2C19LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4520463 | 0.71 | LRRK2 (0.38) | CYP1A2CYP3A4CYP2D6CYP2C19MEN1 | |
| SCHEMBL27319872 | 0.69 | CSNK2A1 (0.54) | CD274CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7625887-B2 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-01 | — | — | US | disclosed |
| US-20060199795-A1 | Receptor agonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-09-07 | — | — | US | disclosed |
| EP-1591120-A1 | RECEPTOR AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199795-A1 | Receptor agonists | GPBAR1, GPR35, GPR55 | ADORA1 129/4885PDCD1 4197/4885CD274 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.