SCHEMBL452408

SCHEMBL452408

CCCCCCCCCCCCCCCCCCOc1cccc(OC(O)CCCCCCCCCCCCCCCCC)c1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.46
CHRM2 P08172 3/20 0.45
LMNA P02545 2/20 0.45
CHRM1 P11229 1/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.45
ACHE P22303 1/20 0.45
KCNH2 Q12809 1/20 0.45
HIF1A Q16665 1/20 0.45
MEN1 O00255 1/20 0.43
NR1I2 O75469 1/20 0.43
CYP3A4 P08684 1/20 0.43
ADRA2A P08913 1/20 0.43
MAPT P10636 1/20 0.43
OPRK1 P41145 1/20 0.43
HTR2B P41595 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KMT2A Q03164 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
PPARA Q07869 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16416819 0.86 CNR1 (0.48) PPARGCHRM2LMNAMEN1NR1I2
SCHEMBL30167843 0.83 CHRM2 (0.56) CHRM2LMNACHRM1ALOX15TSHR
SCHEMBL4527369 0.83 CHRM2 (0.56) CHRM2LMNACHRM1ALOX15TSHR
SCHEMBL453505 0.83 CHRM2 (0.56) CHRM2LMNACHRM1ALOX15TSHR
SCHEMBL456438 0.83 CHRM2 (0.56) CHRM2LMNACHRM1ALOX15TSHR
SCHEMBL30292265 0.82 PPARG (0.41) PPARGCHRM2LMNATSHRMEN1
SCHEMBL19487112 0.78 PPARG (0.56) PPARGCHRM2LMNACHRM1ALOX15
SCHEMBL19612354 0.77 SMN1; SMN2 (0.69) CHRM2LMNACHRM1ALOX15TSHR
SCHEMBL1238407 0.76 LMNA (0.60) CHRM2LMNACHRM1ALOX15TSHR
SCHEMBL453399 0.76 CYP19A1 (0.46) PPARGLMNAMAPTPPARASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968591-B2 Organic piezoelectric material, ultrasound transducer, ultrasound probe, and ultrasound medical diagnostic imaging system KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2015-03-03 US disclosed
US-20120065516-A1 ORGANIC PIEZOELECTRIC MATERIAL, ULTRASOUND TRANSDUCER, ULTRASOUND PROBE, AND ULTRASOUND MEDICAL DIAGNOSTIC IMAGING SYSTEM KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2012-03-15 US disclosed