SCHEMBL453505

SCHEMBL453505

CCCCCCOc1cccc(OCCCCCC)c1OCCCCCC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 3/20 0.56
▸ LMNA P02545 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ CHRM1 P11229 1/20 0.56
▸ ALOX15 P16050 1/20 0.56
▸ ACHE P22303 1/20 0.56
▸ KCNH2 Q12809 1/20 0.56
▸ HIF1A Q16665 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ NR1I2 O75469 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ ADRA2A P08913 1/20 0.53
▸ MAPT P10636 1/20 0.53
▸ OPRK1 P41145 1/20 0.53
▸ HTR2B P41595 1/20 0.53
▸ SLC6A3 Q01959 1/20 0.53
▸ HDAC6 Q9UBN7 1/20 0.53
▸ MCHR1 Q99705 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30167843 1.00 CHRM2 (0.56) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL4527369 1.00 CHRM2 (0.56) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL456438 1.00 CHRM2 (0.56) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL19612354 0.93 SMN1; SMN2 (0.69) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL1238407 0.91 LMNA (0.60) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL11331788 0.89 MCHR1 (0.48) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL8974666 0.89 MCHR1 (0.48) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL19612360 0.88 SMN1; SMN2 (0.52) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL19612363 0.87 L3MBTL1 (0.54) CHRM2LMNATSHRCHRM1ALOX15
SCHEMBL1837216 0.87 LMNA (0.50) CHRM2LMNATSHRCHRM1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011921-B1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION AND ITS METHOD OF MANUFACTURING AND USE IN A TIRE G 3 CHICKADEE PURCHASER LLC 1485 E ARCHWOOD AVENUE (US) 2026-02-04 — — EP disclosed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 — — CN disclosed
US-11912798-B2 Rubber with backbone and end-group functionalization THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-02-27 — — US disclosed
US-20230312798-A1 FUNCTIONALIZED HYDROGENATED POLYMERS MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2023-10-05 — — US disclosed
EP-4011921-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION AND ITS METHOD OF MANUFACTURING AND USE IN A TIRE The Goodyear Tire & Rubber Company (US) 2022-06-15 — — EP disclosed
CN-114621375-A Rubber with main chain and end group functionalization 固特异轮胎和橡胶公司 2022-06-14 — — CN disclosed
US-20220177610-A1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2022-06-09 — — US disclosed
EP-3313927-B1 DILITHIUM INITIATORS FINA TECHNOLOGY (US) 2021-12-15 — — EP disclosed
CN-107922678-B Dilithium initiators 飞纳技术有限公司 2020-04-07 — — CN disclosed
EP-3313927-A1 DILITHIUM INITIATORS Fina Technology, Inc. (US) 2018-05-02 — — EP disclosed
EP-0761703-A1 Isoprene-butadiene diblock rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-03-12 — — EP disclosed
US-5534592-A POLYBUTADIENE RUBBER BLEND THE GOODYEAR TIRE & RUBBER COMPANY (US) 1996-07-09 — — US disclosed
EP-0438967-B1 Segmented elastomer GOODYEAR TIRE & RUBBER (US) 1996-05-01 — — EP disclosed
US-5239009-A Butadiene, isoprene, styrene random polymer, wear resistance, good traction tire treads THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-08-24 — — US disclosed
US-5202387-A Modified styrene-butadiene copolymer; catalytic polymerization using living-catalyst THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-04-13 — — US disclosed
US-5100965-A Process for synthesizing high trans polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-31 — — US disclosed
US-5070148-A SEGMENTED ELASTOMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-03 — — US disclosed
EP-0438967-A1 Segmented elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-07-31 — — EP disclosed
EP-0258167-A2 Modifier for lithium catalysts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-02 — — EP disclosed
US-4696986-A 1,2,3- OR 1,2,4-TRIALKOXYBENZENE MODIFIERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-29 — — US disclosed
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