Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456438 | 1.00 | CHRM2 (0.56) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL30167843 | 1.00 | CHRM2 (0.56) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL453505 | 1.00 | CHRM2 (0.56) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL19612354 | 0.93 | SMN1; SMN2 (0.69) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL1238407 | 0.91 | LMNA (0.60) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL8974666 | 0.89 | MCHR1 (0.48) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL11331788 | 0.89 | MCHR1 (0.48) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL19612360 | 0.88 | SMN1; SMN2 (0.52) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL1837216 | 0.87 | LMNA (0.50) | CHRM2LMNATSHRCHRM1ALOX15 | |
| SCHEMBL1836358 | 0.87 | LMNA (0.50) | CHRM2LMNATSHRCHRM1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176995-A1 | Soluble fullerene derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176995-A1 | Soluble fullerene derivatives | SOD1, EPCAM, NDUFV2 | CHRM2 2152/4885LMNA 3745/4885TSHR 4629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.