Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.44 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65904 | 0.98 | MEN1 (0.47) | MEN1KMT2AGAATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28051579 | 0.96 | MEN1 (0.46) | MEN1KMT2AGAATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29226981 | 0.96 | MEN1 (0.46) | MEN1KMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL7770716 | 0.85 | GAA (0.44) | MEN1KMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL3640178 | 0.83 | ALDH1A1 (0.42) | MEN1KMT2AGAATSHRSMN1; SMN2 | |
| Bromide SCHEMBL10944555 | 0.83 | SMN1; SMN2 (0.49) | MEN1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL3633415 | 0.82 | ALDH1A1 (0.38) | KMT2AGAATSHRPIN1ALDH1A1 | |
| Bromide SCHEMBL29024015 | 0.81 | POLB (0.44) | TSHRSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL14394283 | 0.81 | TSHR (0.51) | MEN1KMT2AGAATSHRSMN1; SMN2 | |
| SCHEMBL21260456 | 0.81 | MEN1 (0.49) | MEN1KMT2AGAATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111592477-A | Novel intermediate compound for preparing norbixin or bixin ethyl ester and preparation method thereof | 明知大学校产学协力团 | 2020-08-28 | — | — | CN | claimed |
| CN-108033902-A | A kind of preparation method of his cis-isomer of high-purity Baily department | 深圳万乐药业有限公司 | 2018-05-15 | — | — | CN | claimed |
| CN-105367455-B | A kind of preparation method of his isomers of Baily department | 深圳万乐药业有限公司 | 2017-10-24 | — | — | CN | claimed |
| CN-105367455-A | Preparation method of Belinostat isomer | SHENZHEN MAIN LUCK PHARMACEUTICALS INC | 2016-03-02 | — | — | CN | claimed |
| CN-117736241-B | Organic-inorganic hybrid perovskite glass material capable of emitting light through long afterglow phosphorescence and preparation method thereof | 北京师范大学 | 2026-05-15 | — | — | CN | disclosed |
| CN-120554416-A | Multimode response manganese-based halide luminescent material, and preparation method and application thereof | 武汉纺织大学 | 2025-08-29 | — | — | CN | disclosed |
| CN-117736241-A | Organic-inorganic hybrid perovskite glass material capable of emitting light through long afterglow phosphorescence and preparation method thereof | 北京师范大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-117177977-A | Bicyclic pyridine derivatives | 住友制药株式会社 | 2023-12-05 | — | — | CN | disclosed |
| CN-113461602-B | Aniline compounds with HDAC (Histone deacetylase) inhibitory activity, preparation method, composition and application | 北京华氏信华科生物科技有限公司 | 2022-06-28 | — | — | CN | disclosed |
| CN-111592477-A | Novel intermediate compound for preparing norbixin or bixin ethyl ester and preparation method thereof | 明知大学校产学协力团 | 2020-08-28 | — | — | CN | disclosed |
| CN-106414434-B | Isothiazole derivatives as GPR120 agonists for the treatment of type II diabetes | 詹森药业有限公司 | 2019-12-31 | — | — | CN | disclosed |
| CN-108033902-A | A kind of preparation method of his cis-isomer of high-purity Baily department | 深圳万乐药业有限公司 | 2018-05-15 | — | — | CN | disclosed |
| CN-105367455-B | A kind of preparation method of his isomers of Baily department | 深圳万乐药业有限公司 | 2017-10-24 | — | — | CN | disclosed |
| CN-105646439-A | Synergist for antifungal drugs, and preparation and application thereof | 中国人民解放军第二军医大学 | 2016-06-08 | — | — | CN | disclosed |
| CN-105367455-A | Preparation method of Belinostat isomer | SHENZHEN MAIN LUCK PHARMACEUTICALS INC | 2016-03-02 | — | — | CN | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | MEN1 1254/4885KMT2A 2379/4885GAA 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.