⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289316 | 0.83 | NOD1 (0.32) | — | |
| SCHEMBL3293801 | 0.77 | SLC6A5 (0.37) | — | |
| SCHEMBL3295257 | 0.69 | EPHX2 (0.35) | — | |
| SCHEMBL6888538 | 0.69 | — | — | |
| SCHEMBL3289310 | 0.67 | DRD2 (0.30) | — | |
| SCHEMBL3293176 | 0.67 | CAPN1 (0.36) | — | |
| SCHEMBL3289720 | 0.66 | CA12 (0.31) | — | |
| SCHEMBL3293189 | 0.65 | CAPN1 (0.39) | — | |
| SCHEMBL3293183 | 0.64 | CA14 (0.35) | — | |
| SCHEMBL3293178 | 0.61 | DRD2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531676-B2 | Lipids | CELLTECH R & D LIMITED (GB) | 2009-05-12 | — | — | US | disclosed |
| US-20040024220-A1 | Lipids | CELLTECH R & D LIMITED | 2004-02-05 | — | — | US | disclosed |
| US-6583301-B1 | Bipolar; form complexes with polyanions; delivering bioactive substances such as nucleic acids to cells in vitro and in vivo | CELLTECH R & D LIMITED (GB) | 2003-06-24 | — | — | US | disclosed |
| EP-1070047-A2 | LIPIDS | Celltech Chiroscience Limited (GB) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052858-A2 | LIPIDS | CELLTECH THERAPEUTICS LIMITED (GB) | 1999-10-21 | — | — | WO | disclosed |