Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13139930 | 0.86 | L3MBTL1 (0.58) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3071849 | 0.84 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL4523306 | 0.84 | GAA (0.60) | L3MBTL1POLBMEN1KMT2AMAPT | |
| SCHEMBL12443197 | 0.83 | L3MBTL1 (0.62) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL3080624 | 0.83 | L3MBTL1 (0.62) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29954498 | 0.81 | L3MBTL1 (0.53) | L3MBTL1ALOX5POLBKMT2AMAPT | |
| SCHEMBL232779 | 0.80 | TP53 (0.64) | TP53ALOX5POLBMEN1KMT2A | |
| SCHEMBL29077532 | 0.79 | KMT2A (0.61) | L3MBTL1TP53POLBMEN1KMT2A | |
| SCHEMBL8374440 | 0.78 | SRD5A2 (0.60) | TP53ALOX5POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2299193 | 0.78 | TP53 (0.62) | TP53ALOX5POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | L3MBTL1 3948/4885HCAR3 400/4885TP53 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.