Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4519480 | 0.90 | PTPRC (0.38) | TAAR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1181113 | 0.90 | TAAR1 (0.41) | TAAR1AOC3L3MBTL1PLAAT3PLAAT5 | |
| SCHEMBL4517362 | 0.84 | TAAR1 (0.40) | TAAR1AOC3L3MBTL1PLAAT3PLAAT5 | |
| SCHEMBL13712818 | 0.83 | TAAR1 (0.39) | TAAR1AOC3L3MBTL1NPC1RAB9A | |
| SCHEMBL13711755 | 0.80 | TAAR1 (0.51) | TAAR1AOC3HTR3EHTR3BHTR3A | |
| SCHEMBL4524801 | 0.80 | PTPRC (0.38) | TAAR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1180759 | 0.80 | TAAR1 (0.39) | TAAR1AOC3L3MBTL1PLAAT3PLAAT5 | |
| SCHEMBL4519449 | 0.78 | TAAR1 (0.43) | TAAR1AOC3PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL18568293 | 0.76 | TAAR1 (0.53) | TAAR1AOC3PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL18567626 | 0.75 | TAAR1 (0.50) | TAAR1AOC3L3MBTL1PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ADRB2, ADRB1, ADRA2C | TAAR1 70/4885AOC3 900/4885L3MBTL1 4422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.