Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TET3 | O43151 | 1/20 | 0.46 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.46 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.46 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.46 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701417 | 0.81 | GRIN2D (0.43) | OPRD1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4537782 | 0.80 | CYP1A2 (0.60) | KMT2ACYP2C19MEN1 | |
| Trifluoroacetic Acid SCHEMBL3070940 | 0.74 | PTPN11 (0.41) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22597907 | 0.74 | GRIN2D (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3078495 | 0.74 | GRIN2D (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL14206533 | 0.73 | GRIN2D (0.42) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10278269 | 0.73 | GRIN2D (0.42) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3436016 | 0.73 | GRIN2D (0.42) | OPRD1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4524152 | 0.72 | NEK2 (0.67) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3422626 | 0.72 | MLYCD (0.53) | OPRD1KMT2AMLYCDCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7501440-B2 | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-03-10 | — | — | US | disclosed |
| US-20040266768-A1 | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266768-A1 | Substituted benzoylureidopyridylpiperidine-and-pyrrolidinecarboxylic acid derivatives, processes for preparing them and their use | SLC5A2, HPD, DPP4 | OPRD1 1527/4885AKR1C1 666/4885KMT2A 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.