SCHEMBL45254

SCHEMBL45254

C=CCNC(=O)Oc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 3/20 0.55
▸ GAA P10253 3/20 0.55
▸ GLA P06280 1/20 0.55
▸ HTT P42858 1/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ ITGB1 P05556 1/20 0.53
▸ ITGA4 P13612 1/20 0.53
▸ ITGB7 P26010 1/20 0.53
▸ ALDH1A1 P00352 3/20 0.50
▸ HPGD P15428 2/20 0.50
▸ LMNA P02545 1/20 0.50
▸ RAD51 Q06609 1/20 0.50
▸ HSD17B10 Q99714 1/20 0.50
▸ MAPT P10636 2/20 0.47
▸ NPC1 O15118 2/20 0.47
▸ POLB P06746 1/20 0.46
▸ CYP1A2 P05177 1/20 0.46
▸ TAAR1 Q96RJ0 2/20 0.45
▸ PKM P14618 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9452176 0.88 ALDH1A1 (0.66) RAB9AGAAGLAHTTSMN1; SMN2
SCHEMBL4563341 0.86 EPHX1 (0.59) —
SCHEMBL1136814 0.85 DRD3 (0.54) RAB9AGAAHTTSMN1; SMN2ALDH1A1
SCHEMBL1136813 0.85 DRD3 (0.54) RAB9AGAAHTTSMN1; SMN2ALDH1A1
SCHEMBL18426755 0.83 TAAR1 (0.50) RAB9AGAAHSD17B10NPC1TAAR1
SCHEMBL9662599 0.83 SMN1; SMN2 (0.52) RAB9AGAAGLAHTTSMN1; SMN2
SCHEMBL21838761 0.82 ALDH1A1 (0.51) RAB9AGAAHTTSMN1; SMN2ALDH1A1
SCHEMBL11465407 0.81 HPGD (0.62) HTTALDH1A1HPGDLMNAPOLB
SCHEMBL11129411 0.80 GAA (0.53) RAB9AGAAGLAHTTSMN1; SMN2
SCHEMBL1416169 0.79 HSD17B10 (0.58) RAB9AGAAHTTALDH1A1RAD51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 772 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11931332-B2 Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease BIO-PHARM SOLUTIONS CO., LTD. (KR) 2024-03-19 — — US claimed
CN-115677609-B Method for cyclizing and cyanating allyl phenyl carbamate derivative 湖北工业大学 2023-10-24 — — CN claimed
CN-110072853-B Herbicidal phenyltriazolinones 巴斯夫欧洲公司 2023-07-25 — — CN claimed
EP-4204395-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISEASE Bio-Pharm Solutions Co., Ltd. (KR) 2023-07-05 — — EP claimed
CN-115677609-A Method for self-cyclizing cyanation of phenyl allyl carbamate derivative 湖北工业大学 2023-02-03 — — CN claimed
US-11185075-B2 Herbicidal phenyltriazolinones BASF SE (DE) 2021-11-30 — — US claimed
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 — — EP claimed
EP-3555053-B1 HERBICIDAL PHENYLTRIAZOLINONES BASF SE (DE) 2021-02-17 — — EP claimed
US-20200085052-A1 Herbicidal Phenyltriazolinones BASF SE (DE) 2020-03-19 — — US claimed
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines BASF SE (DE) 2019-07-02 — — US claimed
WO-2015071087-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE BASF SE (DE) 2015-05-21 — — WO claimed
WO-2014142519-A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 — — WO claimed
CN-103396364-A N-alkyloxy-N-2-[1-(4-halogenated phenyl)-3-pyrazolyloxymethyl]phenylalkyl carbamate UNIV NANJING SCIENCE & TECH 2013-11-20 — — CN claimed
US-8445407-B2 Herbicidal tetrahydrophthalimides BASF SE (DE) 2013-05-21 — — US claimed
EP-2443102-B1 HERBICIDAL BENZOXAZINONES BASF SE (DE) 2013-04-17 — — EP claimed
CN-101680984-B Curable composition for color filter, method for producing curable composition for color filter, colored curable resin composition, method for forming colored pattern, colored pattern, method for prod FUJIFILM CORP 2012-08-08 — — CN claimed
WO-2011067184-A1 3- (4, 5 -DIHYDROISOXAZOL- 5 -YL) BENZOYLPYRAZOLE COMPOUNDS AND MIXTURES THEREOF WITH SAFENERS BASF SE (DE) 2011-06-09 — — WO claimed
CN-101680984-A Curable composition for color filter, method for producing curable composition for color filter, colored curable resin composition, method for forming colored pattern, colored pattern, method for prod FUJIFILM CORP 2010-03-24 — — CN claimed
US-20050090486-A1 Trisubstituted pyrimidines BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-04-28 — — US claimed
US-20030134838-A1 Trisubstituted pyrimidines BOEHRINGER INGELHEIM PHARMA KG (DE) 2003-07-17 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10334851-B2 Herbicidal isoxazolo[5,4-B]pyridines CYP4X1, PNPO, PRDX4 RAB9A 2712/4885GAA 2044/4885GLA 3006/4885
US-11185075-B2 Herbicidal phenyltriazolinones DDT, UPP1, UMPS RAB9A 3869/4885GAA 257/4885GLA 2616/4885
US-20200085052-A1 Herbicidal Phenyltriazolinones DDT, UPP1, UMPS RAB9A 3869/4885GAA 257/4885GLA 2616/4885
US-20030134838-A1 Trisubstituted pyrimidines APP, PSEN1, BACE1 RAB9A 1793/4885GAA 761/4885GLA 1089/4885
US-20050090486-A1 Trisubstituted pyrimidines APP, BACE1, PSEN1 RAB9A 1327/4885GAA 981/4885GLA 1295/4885
US-11931332-B2 Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease SNCA, MAPT, CHAT RAB9A 1763/4885GAA 698/4885GLA 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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