Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2234716 | 0.98 | PKM (0.67) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL12818961 | 0.90 | PKM (0.67) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL10126590 | 0.89 | PKM (0.66) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL30325060 | 0.89 | PKM (0.66) | PKMMAPK1TSHRTP53PLA2G4B | |
| Hydrochloric Acid SCHEMBL15409937 | 0.89 | PKM (0.65) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL14384080 | 0.89 | TP53 (0.67) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL196110 | 0.87 | PKM (0.88) | PKMMAPK1TSHRTP53PLA2G4B | |
| Hydrochloric Acid SCHEMBL28033680 | 0.87 | TP53 (0.65) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL19729157 | 0.85 | RARB (0.67) | PKMMAPK1TSHRTP53PLA2G4B | |
| SCHEMBL118037 | 0.85 | PKM (0.77) | PKMMAPK1TSHRTP53PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357654-B2 | Multimeric CD40 ligands, method for preparing same and use thereof for preparing drugs | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-01-22 | — | — | US | claimed |
| JP-4836455-B2 | — | — | 2011-12-14 | — | — | JP | claimed |
| CN-102167728-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA | 2011-08-31 | — | — | CN | claimed |
| US-7922998-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2011-04-12 | — | — | US | claimed |
| EP-2281580-A2 | Labeled gastrin releasing peptides (GRP) | Bracco Imaging S.p.A (IT) | 2011-02-09 | — | — | EP | claimed |
| US-7850947-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2010-12-14 | — | — | US | claimed |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-07-22 | — | — | US | claimed |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-06-03 | — | — | US | claimed |
| US-7611692-B2 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2009-11-03 | — | — | US | claimed |
| EP-1828240-B1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CENTRE NAT RECH SCIENT (FR) | 2009-07-29 | — | — | EP | claimed |
| US-7226577-B2 | Gastrin releasing peptide compounds | BRACCO IMAGING, S. P. A. (IT) | 2007-06-05 | — | — | US | claimed |
| WO-2007002500-A1 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2007-01-04 | — | — | WO | claimed |
| US-20060239914-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | claimed |
| US-20060239923-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-10-26 | — | — | US | claimed |
| CN-1738650-A | Improved gastrin releasing peptide compounds | BRACCO IMAGING SPA (IT) | 2006-02-22 | — | — | CN | claimed |
| US-20060018830-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2006-01-26 | — | — | US | claimed |
| EP-1585549-A2 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | Bracco Imaging S.p.A. (IT) | 2005-10-19 | — | — | EP | claimed |
| US-20040253225-A1 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | BRACCO IMAGING S.P.A. (IT) | 2004-12-16 | — | — | US | claimed |
| WO-2004065407-A2 | IMPROVED GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2004-08-05 | — | — | WO | claimed |
| US-20040136906-A1 | Gastrin releasing peptide compounds | BRACCO IMAGING S.P.A. (IT) | 2004-07-15 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060239914-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | PKM 3198/4885MAPK1 3495/4885TSHR 136/4885 |
| US-20100183642-A1 | NOVEL MULTIMERIC CD40 LIGANDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR PREPARING DRUGS | CD40, CD40LG, TNFSF10 | PKM 1850/4885MAPK1 2829/4885TSHR 510/4885 |
| US-20040253225-A1 | bombesin, derivatives and/or analogues capable of complexing metal ions, radionuclides or optical labels, for use in radiotherapy | GRPR, MLNR, NPBWR1 | PKM 3994/4885MAPK1 2221/4885TSHR 160/4885 |
| US-20060239923-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | PKM 1756/4885MAPK1 2747/4885TSHR 138/4885 |
| US-20060018830-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, CCKBR | PKM 3198/4885MAPK1 3495/4885TSHR 136/4885 |
| US-20100136034-A1 | NOVEL MULTIMERIC MOLECULES, A PROCESS FOR PREPARING THE SAME AND THE USE THEREOF FOR MANUFACTURING MEDICINAL DRUGS | TNFRSF1A, TNFRSF9, CD40 | PKM 3030/4885MAPK1 2253/4885TSHR 321/4885 |
| US-20040136906-A1 | Gastrin releasing peptide compounds | GRPR, GIPR, MLNR | PKM 3977/4885MAPK1 2145/4885TSHR 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.