Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 4/20 | 0.52 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27858460 | 0.80 | PIK3CA (0.79) | ALDH1A1L3MBTL1KDM4EHTR6PIK3CA | |
| SCHEMBL27949257 | 0.75 | HRH4 (0.59) | ALDH1A1KDM4EHTR3BHTR3AHTR3E | |
| SCHEMBL24971028 | 0.74 | HRH4 (0.65) | ALDH1A1KDM4EHTR3BHTR3AHTR3E | |
| SCHEMBL15865117 | 0.73 | HRH4 (0.54) | ALDH1A1KDM4EHTR3BHTR3AHTR3E | |
| SCHEMBL27840966 | 0.72 | PIK3CA (0.61) | ALDH1A1KDM4EHTR6PIK3CAHTR3B | |
| SCHEMBL27840951 | 0.71 | PIK3CA (0.74) | ALDH1A1KDM4EPIK3CAHTR3BHTR3A | |
| SCHEMBL27858459 | 0.71 | PIK3CA (0.74) | KDM4EHTR6PIK3CAHTR3BHTR3A | |
| SCHEMBL27767388 | 0.70 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1KDM4EHTR6NPSR1 | |
| SCHEMBL27858470 | 0.69 | PIK3CA (0.77) | ALDH1A1KDM4EHTR6PIK3CAHRH4 | |
| SCHEMBL28329085 | 0.69 | KDM4E (0.65) | ALDH1A1KDM4EHTR6NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298841-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS | GLAXO GROUP LIMITED (GB) | 2009-12-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298841-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS 5-HT6 LIGANDS | HTR6, HTR3B, HTR4 | ALDH1A1 2869/4885L3MBTL1 3965/4885KDM4E 3423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.