Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL21834859 | 1.00 | FFAR3 (0.39) | FFAR3LCKFYNCA12CA1 | |
| Bicarbonate SCHEMBL14917 | 0.88 | CA1 (0.38) | CA12CA1CA9POLBALDH1A1 | |
| Bicarbonate SCHEMBL6150295 | 0.88 | CA1 (0.38) | CA12CA1CA9POLBALDH1A1 | |
| SCHEMBL4147046 | 0.86 | GLA (0.31) | CA12CA1CA9GLA | |
| SCHEMBL4147044 | 0.86 | GLA (0.34) | CA12CA1CA9GLAKMT2A | |
| Methacrylic Acid SCHEMBL422938 | 0.85 | KMT2A (0.39) | CA12CA1CA9GLAKMT2A | |
| SCHEMBL785147 | 0.85 | — | — | |
| Carbamic Acid SCHEMBL699756 | 0.83 | ACHE (0.39) | CA12CA1CA9ALDH1A1PKM | |
| SCHEMBL6742810 | 0.83 | CA12 (0.35) | CA12CA1CA9POLBALDH1A1 | |
| Pivalate SCHEMBL10534446 | 0.82 | POLB (0.34) | CA12CA1CA9ATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119280461-A | In-situ cross-linked polypeptide gel and preparation method and application thereof | 江苏德威兰医疗器械股份有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-114438047-B | Method for preparing polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-114438048-B | Urate oxidase preparation and application thereof | 重庆派金生物科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118497161-A | Polyethylene glycol modified urate oxidase | 重庆派金生物科技有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118453890-A | Composition for improving stability of polyethylene glycol asparaginase, pharmaceutical composition and application thereof | 重庆派金生物科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-117866929-A | Pegylated arginine deiminase dimer preparation and use thereof | 重庆派金生物科技有限公司 | 2024-04-12 | — | — | CN | claimed |
| CN-116966279-A | Covalently modified recombinant phenylalanine lyase enteric-coated preparation and application thereof | 重庆派金生物科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116106283-A | Fluorescent analysis method and application of plasmalogens | 清华大学 | 2023-05-12 | — | — | CN | claimed |
| CN-115869456-A | Preparation of in-situ gelation anti-swelling enhanced tissue adhesive material | 上海其胜生物制剂有限公司 | 2023-03-31 | — | — | CN | claimed |
| WO-2022095974-A1 | METHOD FOR PREPARING POLYETHYLENE GLYCOL-MODIFIED URATE OXIDASE | 杭州远大生物制药有限公司 | 2022-05-12 | — | — | WO | claimed |
| CN-111909906-A | Urate oxidase modified by polyethylene glycol | 重庆派金生物科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111868253-A | Method for extracting nucleic acid | 生物梅里埃公司 | 2020-10-30 | — | — | CN | claimed |
| CN-104628006-B | A kind of preparation method of half strawberry type Janus particle | 天津工业大学 | 2019-10-18 | — | — | CN | claimed |
| US-10266819-B2 | Robust, easy to use immobilized enzyme reactors | PERFINITY BIOSCIENCES, INC. (US) | 2019-04-23 | — | — | US | claimed |
| EP-2344200-A2 | MODIFIED THERAPEUTICS PEPTIDES, METHODS OF THEIR PREPARATION AND USE | Nektar Therapeutics (US) | 2011-07-20 | — | — | EP | claimed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | claimed |
| WO-2010033220-A2 | MODIFIED THERAPEUTICS PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2010-03-25 | — | — | WO | claimed |
| EP-1370295-A2 | NEUTRAL AND ANIONIC COLLOIDAL PARTICLES FOR GENE DELIVERY | GENCELL S.A. (FR) | 2003-12-17 | — | — | EP | claimed |
| US-20020146829-A1 | Neutral and anionic colloidal particles for gene delivery | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2002-10-10 | — | — | US | claimed |
| WO-2002043769-A2 | NEUTRAL AND ANIONIC COLLOIDAL PARTICLES FOR GENE DELIVERY | GENCELL S.A. (FR) | 2002-06-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | FFAR3 3053/4885LCK 1709/4885FYN 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.