SCHEMBL4528585

SCHEMBL4528585

C=C[Si](C)(C)CCCCC=O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
HIF1A Q16665 1/20 0.39
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 2/20 0.37
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4525322 0.93 HIF1A (0.41) TSHRHIF1AFAAHTRPV1ALDH1A1
SCHEMBL17628431 0.83
SCHEMBL17628450 0.80
SCHEMBL6909579 0.80
SCHEMBL8159751 0.79 TSHR (0.48) TSHRALDH1A1
SCHEMBL4516728 0.76 HIF1A (0.43) TSHRHIF1AFAAHTRPV1
SCHEMBL18166811 0.73
SCHEMBL10787403 0.73 TSHR (0.52) TSHRHIF1AFAAHTRPV1ALDH1A1
SCHEMBL6567469 0.73 TSHR (0.40) TSHRFAAHALDH1A1
SCHEMBL12354498 0.73 TSHR (0.52) TSHRHIF1AFAAHTRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197903-B2 Surface modified organic inorganic hybrid glass, protecting group induced alcohol or its derivative and producing method thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) 2012-06-12 US disclosed
US-20090274910-A1 Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2009-11-05 US disclosed
WO-2007120014-A1 SURFACE MODIFIED ORGANIC·INORGANIC HYBRID GLASS, PROTECTING GROUP INDUCED ALCOHOL OR ITS DERIVATIVE AND PRODUCING METHOD THEREOF INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) 2007-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090274910-A1 Surface Modified Organic Inorganic Hybrid Glass, Protecting Group Induced Alcohol or Its Derivative and Producing Method Thereof VIM, ICAM1, ILK TSHR 3919/4885HIF1A 3964/4885FAAH 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.