SCHEMBL452863

SCHEMBL452863

CCC(CC)(C(=O)O)C(=O)OC(C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
PTPN1 P18031 1/20 0.36
LMNA P02545 2/20 0.35
HCAR2 Q8TDS4 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6048653 0.89 TSHR (0.42) TSHRPTPN1LMNAHCAR2MEN1
SCHEMBL7503891 0.85 MAPT (0.33) MAPT
SCHEMBL31462323 0.83 LMNA (0.37) TSHRPTPN1LMNAHCAR2MEN1
SCHEMBL3531184 0.83 MAPT (0.34) MEN1KMT2AMAPT
SCHEMBL6048743 0.83 CTSK (0.33)
SCHEMBL27432594 0.83 TSHR (0.37) TSHRPTPN1LMNAHCAR2MEN1
SCHEMBL8404113 0.80 CHRM1 (0.34)
SCHEMBL28363839 0.79 MEN1 (0.43) TSHRPTPN1LMNAMEN1KMT2A
Bicarbonate SCHEMBL28369373 0.79 MMP1 (0.34) TSHRPTPN1LMNAMEN1KMT2A
SCHEMBL27792243 0.78 TSHR (0.37) TSHRPTPN1LMNAHCAR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115449900-B Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2023-11-21 CN claimed
CN-115449900-A Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2022-12-09 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
US-20240191594-A1 Cement Top Jobs In Wellbore Annuli Using Expandable Compositions CHEVRON U.S.A. INC. 2024-06-13 US disclosed
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions CAYMAN CHEMICAL COMPANY, INC. (US) 2024-01-30 US disclosed
US-20240026206-A1 METHODS OF USING EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
US-20240026749-A1 DEPLOYMENT METHODS FOR EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON AUSTRALIA PTY LTD (AU) 2024-01-25 US disclosed
CN-115449900-B Texturing treating agent, preparation method thereof and method for texturing monocrystalline silicon wafer 浙江奥首材料科技有限公司 2023-11-21 CN disclosed
US-20230050318-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS CAYMAN CHEMICAL COMPANY, INC. 2023-02-16 US disclosed
US-11390060-B2 Surface treatment to enhance bonding of composite materials CYTEC INDUSTRIES INC. (US) 2022-07-19 US disclosed
WO-2022132552-A1 DEPLOYMENT METHODS FOR EXPANDABLE POLYMER GROUT FOR PLUG AND ABANDONMENT APPLICATIONS CHEVRON U.S.A. INC. (US) 2022-06-23 WO disclosed
EP-0834519-A1 CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN Japan Polyolefins Co., Ltd. (JP) 1998-04-08 EP disclosed
EP-0739907-A1 An olefin polymerization catalyst and a polyolefin production method TOKUYAMA CORPORATION (JP) 1996-10-30 EP disclosed
US-5482939-A ANTI-PLATELET ACTIVATING FACTOR ACTIVITIES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-01-09 US disclosed
US-5389633-A ANTIASTHMATIC AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
EP-0562439-A1 Triazolopyridazines as antioasthmatics TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-29 EP disclosed
EP-0361365-A1 Aminobenzoic and aminocyclohexane-carboylic acid compounds, compositions, and their method of use E.R. SQUIBB & SONS, INC. (US) 1990-04-04 EP disclosed
EP-0321218-A2 Process for producing polypropylene and stretched polypropylene film MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-21 EP disclosed
US-4824981-A REACTING MALONATES WITH TRIALKYLSILANES, ALKALI METAL AND DIALKYLMALONIC ACID; PURITY DOW CORNING CORPORATION (US) 1989-04-25 US disclosed
EP-0298363-A2 A process to produce silyl ketene acetals DOW CORNING CORPORATION (US) 1989-01-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230050318-A1 DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASES AND CONDITIONS PTGER4, PTGER1, PTGER3 TSHR 554/4885PTPN1 4182/4885LMNA 2913/4885
US-11884624-B2 Difluorolactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions PTGER4, PTGER1, PTGER3 TSHR 554/4885PTPN1 4182/4885LMNA 2913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.