Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.35 |
| ▸ | PRKDC | P78527 | 7/20 | 0.35 |
| ▸ | MTOR | P42345 | 4/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095589 | 0.92 | GAA (0.43) | GAAUSP2AKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL5059322 | 0.67 | TDP2 (0.40) | GAAUSP2MEN1KMT2AALDH1A1 | |
| SCHEMBL5095593 | 0.64 | GAA (0.43) | GAAMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL25634740 | 0.63 | GAA (0.80) | GAAMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL10851025 | 0.60 | GAA (0.60) | GAAMEN1KMT2APRKDCALDH1A1 | |
| SCHEMBL25633969 | 0.60 | GAA (0.65) | GAAMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL502786 | 0.60 | GAA (1.00) | GAAMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL6999192 | 0.60 | GAA (0.75) | GAAMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL2952972 | 0.60 | GAA (0.75) | GAAMEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL10834109 | 0.60 | CDC25B (0.65) | GAAAKR1C3AKR1C2ALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498341-B2 | antidiabetic agents; type 2 diabetes | SANOFI AVENTIS DEUTSCHLAND GMBH (DE) | 2009-03-03 | — | — | US | disclosed |
| US-7402674-B2 | 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | SANOFI-AVENTIS DEUTSCHLAND GMBH, (DE) | 2008-07-22 | — | — | US | disclosed |
| US-20050182085-A1 | 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-08-18 | — | — | US | disclosed |
| US-20050182086-A1 | antidiabetic agents; type 2 diabetes | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050182086-A1 | antidiabetic agents; type 2 diabetes | SLC5A2, SLC5A1, SLC2A2 | GAA 671/4885USP2 2175/4885MEN1 2746/4885 |
| US-20050182085-A1 | 7-phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments | SLC5A2, CYP2A7, GLS | GAA 413/4885USP2 2156/4885MEN1 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.