Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.63 |
| ▸ | CA2 | P00918 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | ABAT | P80404 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23660445 | 0.82 | EPHX2 (0.53) | L3MBTL1EPHX2MAPTHTTRECQL | |
| SCHEMBL14107963 | 0.82 | MAPT (0.58) | L3MBTL1EPHX2MAPTRECQLSMN1; SMN2 | |
| Acetanilide SCHEMBL11221126 | 0.82 | NAPRT (0.73) | L3MBTL1ABATMAPTHTTEPHX1 | |
| SCHEMBL27852723 | 0.81 | RECQL (0.74) | EPHX2MAPTHTTRECQLMEN1 | |
| SCHEMBL5913640 | 0.81 | HDAC1 (0.55) | CA1CA2L3MBTL1EPHX2MAPT | |
| SCHEMBL2555157 | 0.80 | CA1 (0.59) | CA1CA2MAPTSMN1; SMN2MEN1 | |
| SCHEMBL15332168 | 0.80 | KMT2A (0.62) | CA1CA2L3MBTL1MAPTHTT | |
| SCHEMBL28961967 | 0.79 | ALDH1A1 (0.51) | L3MBTL1EPHX2MAPTHTTRECQL | |
| SCHEMBL8520467 | 0.79 | KDM4E (0.59) | L3MBTL1EPHX2MAPTHTTRECQL | |
| SCHEMBL23178156 | 0.79 | GAA (0.67) | L3MBTL1EPHX2MAPTRECQLHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102653158-B | Lithographic printing plate precursor and plate making method thereof | FUJIFILM CORP | 2015-04-15 | — | — | CN | disclosed |
| US-8314121-B2 | Imidazolone derivatives, preparation thereof as drugs, pharmaceutical compositions, and use thereof as protein kinase inhibitors, in particular CDC7 | SANOFI (FR) | 2012-11-20 | — | — | US | disclosed |
| CN-102653158-A | Lithographic printing plate precursor and plate making method thereof | FUJIFILM CORP | 2012-09-05 | — | — | CN | disclosed |
| US-20090253679-A1 | NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7 | SANOFI-AVENTIS (FR) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253679-A1 | NEW IMIDAZOLONE DERIVATIVES, PREPARATION THEREOF AS DRUGS, PHARMACEUTICAL COMPOSITIONS, AND USE THEREOF AS PROTEIN KINASE INHIBITORS, IN PARTICULAR CDC7 | CDC7, CDK7, CDK17 | CA1 4606/4885CA2 3446/4885L3MBTL1 4256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.