Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520467 | 0.85 | KDM4E (0.59) | EPHX2L3MBTL1HDAC1HDAC3HDAC4 | |
| SCHEMBL4529276 | 0.82 | CA1 (0.63) | EPHX2L3MBTL1HDAC1MAPTRECQL | |
| SCHEMBL14107963 | 0.81 | MAPT (0.58) | EPHX2L3MBTL1MAPTRECQLMEN1 | |
| SCHEMBL6018151 | 0.81 | EPHX2 (0.53) | EPHX2L3MBTL1HDAC1HDAC3HDAC4 | |
| SCHEMBL4844265 | 0.80 | MAOB (0.62) | EPHX2L3MBTL1HDAC1HDAC3HDAC4 | |
| SCHEMBL27852723 | 0.79 | RECQL (0.74) | EPHX2MAPTRECQLHTTMEN1 | |
| SCHEMBL5913640 | 0.79 | HDAC1 (0.55) | EPHX2L3MBTL1HDAC1HDAC3HDAC4 | |
| SCHEMBL23178156 | 0.78 | GAA (0.67) | EPHX2L3MBTL1HDAC1HDAC3HDAC2 | |
| SCHEMBL28961967 | 0.78 | ALDH1A1 (0.51) | EPHX2L3MBTL1HDAC1HDAC3HDAC4 | |
| SCHEMBL11458040 | 0.78 | L3MBTL1 (0.66) | EPHX2L3MBTL1HDAC1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143762-A1 | NOVEL COMPOUNDS AS INHIBITORS OF PCSK9 | SHENGKE PHARMACEUTICALS (JIANGSU) LTD. (CN) | 2021-07-22 | — | — | WO | disclosed |