SCHEMBL4529436

SCHEMBL4529436

CCc1cc(-c2ccccc2)c(CC)c(CC)c1CC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
RECQL P46063 1/20 0.38
PTGS1 P23219 1/20 0.38
BACE1 P56817 2/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
DPP4 P27487 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
GCGR P47871 1/20 0.36
USP7 Q93009 2/20 0.36
HPGD P15428 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 1/20 0.35
FOLH1 Q04609 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
LTB4R Q15722 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31549864 0.96 SMN1; SMN2 (0.41) SMN1; SMN2POLBRECQLPTGS1ESR1
SCHEMBL11198850 0.85 SLC5A2 (0.42) PTGS1TP53
SCHEMBL11022297 0.83 PTPN1 (0.42) SMN1; SMN2POLBRECQLPTGS1BACE1
SCHEMBL473259 0.82 DPP4 (0.38) SMN1; SMN2POLBRECQLPTGS1BACE1
SCHEMBL30112562 0.81 BACE1 (0.44) SMN1; SMN2PTGS1BACE1ESR2DPP4
Water SCHEMBL474768 0.80 DPP4 (0.37) SMN1; SMN2POLBRECQLPTGS1ESR1
SCHEMBL29068247 0.77 PTGS1 (0.44) SMN1; SMN2POLBRECQLPTGS1BACE1
SCHEMBL27449055 0.76 ALDH1A1 (0.46) SMN1; SMN2POLBRECQLL3MBTL1KMT2A
SCHEMBL2870897 0.76 HDAC4 (0.44) SMN1; SMN2POLBRECQLPTGS1BACE1
SCHEMBL25144837 0.76 LTB4R (0.42) SMN1; SMN2POLBRECQLPDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724765-A Method for preparing sulfonamide derivative by using low-cost metal catalysis 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-10-01 CN claimed
EP-3274318-B1 PRODUCTION OF BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-02-26 EP claimed
EP-3274318-A1 PRODUCTION OF BIPHENYL COMPOUNDS ExxonMobil Chemical Patents Inc. (US) 2018-01-31 EP claimed
CN-107428630-A The production of biphenol compound 埃克森美孚化学专利公司 2017-12-01 CN claimed
US-9708230-B2 Production of biphenyl compounds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-07-18 US claimed
WO-2016153575-A1 PRODUCTION OF BIPHENYL COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-09-29 WO claimed
US-20160280616-A1 Production of Biphenyl Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2016-09-29 US claimed
EP-0347500-B1 METHOD OF MAKING ETHYLBIPHENYLS NIPPON STEEL CHEMICAL CO., LTD. (JP) 1993-08-25 EP claimed
US-4943553-A ETHYLATION TRANSETHYLATION NIPPON STEEL CHEMICAL CO., LTD. (JP) 1990-07-24 US claimed
EP-0347500-A1 Method of making ethylbiphenyls NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-12-27 EP claimed
US-12516147-B2 Aldimines and uses thereof BOSTIK SA (FR) 2026-01-06 US disclosed
EP-4617336-A1 TWO-COMPONENT COMPOSITION Bostik SA (FR) 2025-09-17 EP disclosed
EP-4077273-B1 ALDIMINES AND USES THEREOF BOSTIK SA (FR) 2025-04-02 EP disclosed
US-20250034440-A1 (METH)ACRYLATE-BASED TWO-COMPONENT ADHESIVE FORMULATION FOR ASSEMBLING WIND TURBINE BLADES BOSTIK SA (FR) 2025-01-30 US disclosed
US-12152175-B2 Composition made from (meth)acrylate monomers BOSTIK SA (FR) 2024-11-26 US disclosed
US-4917848-A HIGH TENACITY AND HIGH MODULUS TOYO BOSEKI KABUSHIKI KAISHA (JP) 1990-04-17 US disclosed
EP-0207856-B1 PROCESS FOR THE PREPARATION OF ULTRA HIGH MOLECULAR WEIGHT POLYESTERS Toyo Boseki Kabushiki Kaisha (JP) 1990-04-04 EP disclosed
EP-0347500-A1 Method of making ethylbiphenyls NIPPON STEEL CHEMICAL CO., LTD. (JP) 1989-12-27 EP disclosed
US-4742151-A HIGH VISCOSITY BUT SOLVENT-SOLUBLE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1988-05-03 US disclosed
EP-0207856-A1 Process for the preparation of ultra high molecular weight polyesters Toyo Boseki Kabushiki Kaisha (JP) 1987-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280616-A1 Production of Biphenyl Compounds AHR, ARNT, CYP1B1 SMN1; SMN2 3260/4885POLB 1414/4885RECQL 4454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.