Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347327 | 0.93 | THRB (0.46) | THRATHRB | |
| SCHEMBL5487939 | 0.90 | THRA (0.59) | THRATHRB | |
| SCHEMBL4353708 | 0.86 | THRA (0.64) | THRATHRB | |
| SCHEMBL5964571 | 0.82 | THRA (0.55) | THRATHRB | |
| SCHEMBL5287547 | 0.81 | THRB (0.73) | THRATHRB | |
| SCHEMBL5281234 | 0.77 | THRA (0.70) | THRATHRB | |
| SCHEMBL5292931 | 0.76 | THRA (0.62) | THRATHRB | |
| SCHEMBL5618151 | 0.75 | THRA (0.61) | THRATHRB | |
| SCHEMBL5275174 | 0.74 | THRA (0.59) | THRATHRB | |
| SCHEMBL5278519 | 0.74 | THRB (0.43) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862450-A2 | Novel compounds | KARO BIO AB (SE) | 2007-12-05 | — | — | EP | claimed |
| EP-1537073-B1 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KAROBIO AB (SE) | 2007-09-12 | — | — | EP | claimed |
| US-7153997-B2 | Benzamide derivatives as thyroid receptor ligands | KARO BIO AB (SE) | 2006-12-26 | — | — | US | claimed |
| US-20060135614-A1 | Novel compounds | NORIN, THOMAS ANDERS WILSON (SE) | 2006-06-22 | — | — | US | claimed |
| EP-2029616-A1 | CHEMICAL METHODS AND APPARATUS | Hammersmith Imanet Limited (GB) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007148074-A1 | CHEMICAL METHODS AND APPARATUS | HAMMERSMITH IMANET LIMITED (GB) | 2007-12-27 | — | — | WO | disclosed |
| EP-1862450-A2 | Novel compounds | KARO BIO AB (SE) | 2007-12-05 | — | — | EP | disclosed |
| EP-1537073-B1 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KAROBIO AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| US-7153997-B2 | Benzamide derivatives as thyroid receptor ligands | KARO BIO AB (SE) | 2006-12-26 | — | — | US | disclosed |
| US-20060135614-A1 | Novel compounds | NORIN, THOMAS ANDERS WILSON (SE) | 2006-06-22 | — | — | US | disclosed |
| EP-1537073-A2 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004007430-A2 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135614-A1 | Novel compounds | THRB, TSHR, THRA | THRA 3/4885THRB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.