Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclobarbital SCHEMBL157224 | 0.88 | MEN1 (0.44) | HCAR2MEN1KMT2AMMP2MMP3 | |
| Heptabarbital SCHEMBL713359 | 0.86 | MEN1 (0.43) | HCAR2MEN1KMT2AMMP2MMP3 | |
| Cyclobarbital SCHEMBL1256543 | 0.86 | MEN1 (0.43) | HCAR2MEN1KMT2AMMP2MMP3 | |
| Cyclobarbital SCHEMBL7698655 | 0.85 | MEN1 (0.42) | HCAR2MEN1KMT2AMMP2MMP3 | |
| Cyclobarbital SCHEMBL22231503 | 0.82 | AKR1B1 (0.39) | HCAR2MEN1KMT2AMMP2MMP3 | |
| Cyclobarbital SCHEMBL7617865 | 0.76 | MEN1 (0.31) | MEN1KMT2A | |
| Cyclobarbital SCHEMBL4752649 | 0.75 | MEN1 (0.33) | MEN1KMT2AMMP2MMP3MMP9 | |
| SCHEMBL11561765 | 0.74 | MMP9 (0.35) | MEN1KMT2AMMP9 | |
| Mephobarbital SCHEMBL4261724 | 0.73 | LMNA (0.65) | MEN1KMT2AMMP2MMP3MMP9 | |
| Phenobarbital SCHEMBL18222943 | 0.72 | MMP9 (0.63) | HCAR2MEN1KMT2AMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070166532-A1 | SYSTEM FOR USE IN A POLYMERIC FORMULATION | BORDENER ROBERT | 2007-07-19 | — | — | US | disclosed |
| US-20070090553-A1 | Method for Preparing a Polymeric Article | BORDENER ROBERT | 2007-04-26 | — | — | US | disclosed |
| US-20040126571-A1 | Plastic material with decorative attributes | BORDENER ENGINEERED LAMINATES, INC. | 2004-07-01 | — | — | US | disclosed |